ArticleAntimicrobial agents and chemotherapy2014
Antibacterial properties of magnesium in vitro and in an in vivo model of implant-associated methicillin-resistant Staphylococcus aureus infection.
Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Current therapeutic interventions combating biofilm-related infections in orthopaedics : a systematic review of in vivo animal studies.Bone & joint research · 2022Pooled it
- Peri-Implantitis-An Overview of Treatment Options and a New Approach to the Treatment of Peri-Implantitis Using a Magnesium Membrane in Three Case Reports.Dentistry journal · 2026Review
- Functional biomaterials for the treatment of periprosthetic joint infection: A systematic review of preclinical animal studies.Journal of orthopaedic translation · 2026Review
- Magnesium as an emerging bioactive material for orthopedic applications: bedside needs lead the way from innovation to clinical translation.Regenerative biomaterials · 2025Review
- Current and promising applications of MOF composites in the healing of diabetes wounds.RSC medicinal chemistry · 2024Review
- Dynamic Adhesive Behavior and Biofilm Formation ofMaterials (Basel, Switzerland) · 2024Article
- Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview.International journal of molecular sciences · 2024Review
- Multifaceted Materials for Enhanced Osteogenesis and Antimicrobial Properties on Bioplastic Polyetheretherketone Surfaces: A Review.ACS omega · 2024Review
- Preparation of a novel antibacterial magnesium carbonate coating on a titanium surface and itsRSC advances · 2024Article
- Albumin Protein Impact on Early-StageACS applied materials & interfaces · 2024Article
- Collagen membrane functionalized with magnesium oxide via room-temperature atomic layer deposition promotes osteopromotive and antimicrobial properties.Bioactive materials · 2023Article
- Corrosion of an AZ31B Magnesium Alloy by Sulfate-Reducing Prokaryotes in a Mudflat Environment.Microorganisms · 2022Article
- Phenolic Contents, Organic Acids, and the Antioxidant and Bio Activity of Wild Medicinal Berberis Plants- as Sustainable Sources of Functional Food.Molecules (Basel, Switzerland) · 2022Article
- Bone Union Quality after Fracture Fixation of Mandibular Head with Compression Magnesium Screws.Materials (Basel, Switzerland) · 2022Article
- Additively manufactured biodegradable porous magnesium implants for elimination of implant-related infections: AnBioactive materials · 2022Article
- Mg-, Zn-, and Fe-Based Alloys With Antibacterial Properties as Orthopedic Implant Materials.Frontiers in bioengineering and biotechnology · 2022Review
- Biochemical profile of paediatric adamantinomatous craniopharyngiomas: A prospective cohort study.Frontiers in surgery · 2022Article
- Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated InfectionsACS infectious diseases · 2021Review
- Characterization and in vitro assessment of three-dimensional extrusion Mg-Sr codoped SiOBiomedical engineering online · 2021Article
- Two-Step Approach Using Degradable Magnesium to Inhibit Surface Biofilm and Subsequently Kill Planktonic Bacteria.Biomedicines · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic infection remains a challenging clinical complication. We investigated the antibacterial properties of pure (99.9%) magnesium (Mg) in vitro and in an in vivo rat model of implant-related infection. Mg was highly effective against methicillin-resistant Staphylococcus aureus-induced osteomyelitis and improved new peri-implant bone formation. Bacterial icaA and agr RNAIII transcription levels were also assessed to characterize the mechanism underlying the antibacterial properties of the Mg implant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.