ArticleInternational journal of obesity (2005)2015
Natural course of metabolically healthy abdominal obese adults after 10 years of follow-up: the Tehran Lipid and Glucose Study.
Article in International journal of obesity (2005), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Metabolic phenotypes and risk of colorectal cancer: a systematic review and meta-analysis of cohort studies.BMC cancer · 2022Pooled it
- Metabolic phenotypes of obese, overweight, and normal weight individuals and risk of chronic kidney disease: a systematic review and meta-analysis.Archives of endocrinology and metabolism · 2019Pooled it
- Trial
- The Effect of Aerobic or Aerobic-Strength Exercise on Body Composition and Functional Capacity in Patients with BMI ≥35 after Bariatric Surgery: a Randomized Control Trial.Obesity surgery · 2017Trial
- Metabolic phenotypes of obesity: frequency, correlates and change over time in a cohort of postmenopausal women.International journal of obesity (2005) · 2017Trial
- Research on Obesity: A Quarter-Century Experience from the Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2026Review
- Article
- High prevalence of metabolic obesity in India: The ICMR-INDIAB national study (ICMR-INDIAB-23).The Indian journal of medical research · 2025Article
- Relationship of different metabolic obesity phenotypes with reflux esophagitis: a propensity score matching analysis.BMC endocrine disorders · 2024Article
- Gut microbiome signature of metabolically healthy obese individuals according to anthropometric, metabolic and inflammatory parameters.Scientific reports · 2024Article
- Association Between Different Metabolic Obesity Phenotypes and Erosive Esophagitis: A Retrospective Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Association of Lifelines Diet Score (LLDS) and metabolically unhealthy overweight/obesity phenotypes in women: a cross-sectional study.BMC women's health · 2022Article
- Abdominal obesity phenotypes are associated with the risk of developing non-alcoholic fatty liver disease: insights from the general population.BMC gastroenterology · 2022Article
- Selected Organ and Endocrine Complications According to BMI and the Metabolic Category of Obesity: A Single Endocrine Center Study.Nutrients · 2022Article
- Transition patterns of metabolism-weight phenotypes over time: A longitudinal study using the multistate Markov model in China.Frontiers in public health · 2022Article
- The effects of a 5-year physical activity on prescription (PAP) intervention in patients with metabolic risk factors.PloS one · 2022Article
- Are Abdominal Obese Metabolically Healthy Phenotype a Benign Condition? Protocol for a Systematic Review.International journal of preventive medicine · 2022Review
- Wrist circumference as a novel predictor of transition from metabolically healthy to unhealthy phenotype in overweight/obese adults: a gender-stratified 15.5-year follow-up.BMC public health · 2021Article
- Natural course of metabolically healthy phenotype and risk of developing Cardiometabolic diseases: a three years follow-up study.BMC endocrine disorders · 2021Article
- Metabolically healthy obesity and metabolically obese normal weight: a review.Journal of physiology and biochemistry · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to assess the natural course of metabolically healthy abdominal obese (MHAO) phenotype and determine the predictors of change in the metabolic status in this population over 10 years of follow-up.
methodsA total of 916 MHAO subjects from the Tehran Lipid and Glucose Study were followed for changes in their metabolic health status. Anthropometric and metabolic indices were measured at baseline and were compared between subjects with healthy and unhealthy metabolic conditions at the end of follow-up. Predictors of change in metabolic health were assessed in logistic regression models. National waist circumference cutoffs were used for definition of abdominal obesity. Metabolic health was defined as ⩽1 metabolic components of metabolic syndrome according to the Joint Interim Statement criteria.
resultsAt the end of the follow-up, nearly half of the MHAO subjects lost their metabolic health and 42.1% developed metabolic syndrome by definition. Low high-density lipoprotein cholesterol, hypertriglyceridemia and homeostasis model assessment-insulin resistance at baseline were significant predictors of change in metabolic health condition.
conclusionMHAO is a relatively unstable condition and a considerable percentage of these individuals will lose their metabolic health as time passes. Baseline metabolic characteristics may be useful predictors of this change and should be considered in the care of these individuals.
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