Evidence map›Paper›PMID 25286849›Full record

ArticleActa crystallographica. Section D, Biological crystallography2014

New methods for indexing multi-lattice diffraction data.

Richard J Gildea, David G Waterman, James M Parkhurst, Danny Axford, Geoff Sutton, David I Stuart, Nicholas K Sauter, Gwyndaf Evans, Graeme Winter

Abstract read
In one paragraph

Article in Acta crystallographica. Section D, Biological crystallography, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Capturing irreversible photoswitching inChemical communications (Cambridge, England) · 2026
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  5. bioRxiv : the preprint server for biology · 2025
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  7. Journal of applied crystallography · 2024
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  8. Article
  9. Deep residual networks for crystallography trained on synthetic data.Acta crystallographica. Section D, Structural biology · 2024
    Article
  10. Article
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  12. DIALS as a toolkit.Protein science : a publication of the Protein Society · 2022
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Richard J GildeaDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.
David G WatermanSTFC Rutherford Appleton Laboratory, Didcot OX11 0QX, England.
James M ParkhurstDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.
Danny AxfordDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.
Geoff SuttonDivision of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, England.
David I StuartDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.
Nicholas K SauterPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Gwyndaf EvansDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.
Graeme WinterDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.

Funding

Realizing New Horizons in X-ray Crystallography Data ProcessingR01GM095887 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI SAUTER, NICHOLAS K · 2011 to 2014
$1.5M
Medical Research Council G1000099Medical Research Council G19/3NIGMS NIH HHS GM095887NIGMS NIH HHS R01 GM095887
6 · The paper itself

Abstract

A new indexing method is presented which is capable of indexing multiple crystal lattices from narrow wedges of diffraction data. The method takes advantage of a simplification of Fourier transform-based methods that is applicable when the unit-cell dimensions are known a priori. The efficacy of this method is demonstrated with both semi-synthetic multi-lattice data and real multi-lattice data recorded from crystals of ∼1 µm in size, where it is shown that up to six lattices can be successfully indexed and subsequently integrated from a 1° wedge of data. Analysis is presented which shows that improvements in data-quality indicators can be obtained through accurate identification and rejection of overlapping reflections prior to scaling.

Indexed as

AlgorithmsAbstracting and IndexingCrystallography, X-RayDatabases, ProteinFourier AnalysisProteinsX-Ray DiffractionProteinsindexingmulti-lattice data

Identifiers

PMID25286849
PMCPMC4188007

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.