ArticlePloS one2014
Caspase-like activities accompany programmed cell death events in developing barley grains.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
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- Ectopic expression of a human cysteine aspartate-specific protease genePlant biotechnology (Tokyo, Japan) · 2026Article
- Plant caspase-like proteins: from function identification to application in winter rapeseed genetic breeding.Frontiers in plant science · 2026Review
- Extracellular Compounds from Pathogenic BacteriumBiology · 2022Article
- Melatonin Protects Tobacco Suspension Cells against Pb-Induced Mitochondrial Dysfunction.International journal of molecular sciences · 2021Article
- Morphological and Ultrastructural Features of Formation of the Skin of Wheat (Plants (Basel, Switzerland) · 2021Article
- Programmed Cell Death in DevelopingInternational journal of molecular sciences · 2021Article
- Spatial distribution of proteins and metabolites in developing wheat grain and their differential regulatory response during the grain filling process.The Plant journal : for cell and molecular biology · 2021Article
- Short-term waterlogging-induced autophagy in root cells of wheat can inhibit programmed cell death.Protoplasma · 2021Article
- Article
- Grain filling in barley relies on developmentally controlled programmed cell death.Communications biology · 2021Article
- TMT-Based Quantitative Proteomic Analysis Reveals the Physiological Regulatory Networks of Embryo Dehydration Protection in Lotus (Frontiers in plant science · 2021Article
- The highly divergent Jekyll genes, required for sexual reproduction, are lineage specific for the related grass tribes Triticeae and Bromeae.The Plant journal : for cell and molecular biology · 2019Article
- Plant proteases during developmental programmed cell death.Journal of experimental botany · 2019Review
- Plant Vacuolar Processing Enzymes.Frontiers in plant science · 2019Review
- Natural Variation in Ovule Morphology Is Influenced by Multiple Tissues and Impacts Downstream Grain Development in Barley (Frontiers in plant science · 2019Article
- Seed tissue and nutrient partitioning, a case for the nucellus.Plant reproduction · 2018Review
- Article
- Rice caryopsis development I: Dynamic changes in different cell layers.Journal of integrative plant biology · 2016Article
- Bcl-2△21 and Ac-DEVD-CHO Inhibit Death of Wheat Microspores.Frontiers in plant science · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programmed cell death is essential part of development and cell homeostasis of any multicellular organism. We have analyzed programmed cell death in developing barley caryopsis at histological, biochemical and molecular level. Caspase-1, -3, -4, -6 and -8-like activities increased with aging of pericarp coinciding with abundance of TUNEL positive nuclei and expression of HvVPE4 and HvPhS2 genes in the tissue. TUNEL-positive nuclei were also detected in nucellus and nucellar projection as well as in embryo surrounding region during early caryopsis development. Quantitative RT-PCR analysis of micro-dissected grain tissues revealed the expression of HvVPE2a, HvVPE2b, HvVPE2d, HvPhS2 and HvPhS3 genes exclusively in the nucellus/nucellar projection. The first increase in cascade of caspase-1, -3, -4, -6 and -8-like activities in the endosperm fraction may be related to programmed cell death in the nucellus and nucellar projection. The second increase of all above caspase-like activities including of caspase-9-like was detected in the maturating endosperm and coincided with expression of HvVPE1 and HvPhS1 genes as well as with degeneration of nuclei in starchy endosperm and transfer cells. The distribution of the TUNEL-positive nuclei, tissues-specific expression of genes encoding proteases with potential caspase activities and cascades of caspase-like activities suggest that each seed tissue follows individual pattern of development and disintegration, which however harmonizes with growth of the other tissues in order to achieve proper caryopsis development.
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