ReviewChemical Society reviews2015
Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules.
Review in Chemical Society reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
250 citing papers in PubMed, 1,621 citations in OpenAlex.
- Ratiometric Fluorescence Sensing of Aflatoxin B1 Using a Cationic Perylene Probe and Rhodamine B.Journal of fluorescence · 2026Article
- The multifaceted significance of phosphoinositides in endocytic trafficking.FEBS letters · 2026Review
- Twisted Intramolecular Charge Shuttle (TICS) Enables Ultrafast Ratiometric Sensing and Imaging of Nitrite.Angewandte Chemie (International ed. in English) · 2026Article
- Small Organic Molecule-Based Multicolor Fluorescent Smart Materials: From Design Principles and Optical Properties to Versatile Applications.ACS central science · 2026Review
- Functional DNAzyme-Guided Target Identification and Portable Detection of Colorectal Cancer.JACS Au · 2026Article
- Bright Solvatochromic Fluorophores With Dual Emission Enabled by a Donor-Engineering Strategy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Ratiometric photoelectrochemical sensors: advances in food analysis and emerging applications.Analytical and bioanalytical chemistry · 2026Review
- Carbon Quantum Dot-Based Sensors: Photochemical Principles and Multimodal Applications.Materials (Basel, Switzerland) · 2026Review
- Induced-Fit Recognition by a Calixarene-Pyrene Conjugate for Single- and Dual-Wavelength Fluorescence Sensing in Water.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Molecular Design Strategies Enabling Activity-Based Sensing and Labeling as a Platform for Probing Enzyme Activity, Redox Regulation, and Transition-Metal Signaling.Bioconjugate chemistry · 2026Review
- A near-infrared ratio fluorescent probe achieves mitochondrial hydrogen polysulfide imaging for monitoring ferroptosis in arthritis.Synthetic and systems biotechnology · 2026Article
- In Situ, Real-Time Imaging of pH Gradients and Solution Flows through Silica Garden Membranes during Tube Growth.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Advances in Coumarin Fluorescent Probes for Medical Diagnostics: A Review of Recent Developments.Biosensors · 2026Review
- Mitochondria and Lysosome-Targeted Luminescent Iridium(III) Probe for Selective Detection of HgChemistry, an Asian journal · 2026Article
- Multiscale tracking of emulsion dynamics by aggregation-induced emission.National science review · 2025Article
- Detection of explosive picric acidRSC advances · 2025Article
- Pull-Push Interaction between Ions and Synthetic Polymers in All-Fiber Triboelectric Nanogenerators for Wireless Healthcare Applications.ACS omega · 2025Article
- Fluorescent Chemosensors in the Detection of Ultra-trace Quantity of Toxic HgJournal of fluorescence · 2025Review
- Single molecule spectrum dynamics imaging with 3D target-locking tracking.Nature communications · 2025Article
- Design, Synthesis and Sensing Application of Novel Dual Lanthanide Doped Core-Shell Fluorescent Silica-Based Nanoparticles.Biosensors · 2025Article
190 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Quantitative determination of specific analytes is essential for a variety of applications ranging from life sciences to environmental monitoring. Optical sensing allows non-invasive measurements within biological milieus, parallel monitoring of multiple samples, and less invasive imaging. Among the optical sensing methods currently being explored, ratiometric fluorescence sensing has received particular attention as a technique with the potential to provide precise and quantitative analyses. Among its advantages are high sensitivity and inherent reliability, which reflect the self-calibration provided by monitoring two (or more) emissions. A wide variety of ratiometric sensing probes using small fluorescent molecules have been developed for sensing, imaging, and biomedical applications. In this research highlight, we provide an overview of the design principles underlying small fluorescent probes that have been applied to the ratiometric detection of various analytes, including cations, anions, and biomolecules in solution and in biological samples. This highlight is designed to be illustrative, not comprehensive.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.