Evidence map›Paper›PMID 25285541›Full record

ArticleAnnals of internal medicine2014

Physician decision making and trends in the use of cardiac stress testing in the United States: an analysis of repeated cross-sectional data.

Joseph A Ladapo, Saul Blecker, Pamela S Douglas

Registry-linked trialAbstract read
In one paragraph

Article in Annals of internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04647448 (Multisensor Array for the Localisation of Coronary Artery Stenosis), which is not on this map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647448 withdrawnnot on this mapstarted 2025, after this paper: background citation

Multisensor Array for the Localisation of Coronary Artery Stenosis

TypeobservationalSponsorBarts & The London NHS TrustRan2025 to 2026Enrolled0ConditionsCORONARY ARTERY DISEASEArmsApplication of sensor patch
3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 159 citations in OpenAlex.

  1. Social disparities in patient safety in primary care: a systematic review.International journal for equity in health · 2018
    Pooled it
  2. Pooled it
  3. Cardiac testing choices by physician specialty in the CMR-IMPACT trial.The American journal of emergency medicine · 2025
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  12. Repositioning of exercise treadmill testing in contemporary chest pain management.The international journal of cardiovascular imaging · 2026
    Review
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  14. Observational
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  17. Review
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joseph A Ladapo
Saul Blecker
Pamela S Douglas
Duke University · US

Funding

Institutional Clinical and Translational Science AwardKL2TR000053 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2012 to 2014
$899k
Patient-centered approaches to diagnosing coronary heart diseaseK23HL116787 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LADAPO, JOSEPH ABIODUN · 2013 to 2017
$790k
Health Information Technology in Heart Failure CareK08HS023683 · AHRQ · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BLECKER, SAUL B. · 2014 to 2017
$633k
AHRQ HHS K08 HS023683NCATS NIH HHS KL2 TR000053NHLBI NIH HHS 1 K23 HL116787-01A1NHLBI NIH HHS K23 HL116787
6 · The paper itself

Abstract

backgroundCardiac stress testing, particularly with imaging, has been the focus of debates about rising health care costs, inappropriate use, and patient safety in the context of radiation exposure.

objectiveTo determine whether U.S. trends in cardiac stress test use may be attributable to population shifts in demographics, risk factors, and provider characteristics and evaluate whether racial/ethnic disparities exist in physician decision making.

designAnalyses of repeated cross-sectional data.

settingNational Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey (1993 to 2010). PATIENTS: Adults without coronary heart disease. MEASUREMENTS: Cardiac stress test referrals and inappropriate use.

resultsBetween 1993 to 1995 and 2008 to 2010, the annual number of U.S. ambulatory visits in which a cardiac stress test was ordered or performed increased from 28 per 10,000 visits to 45 per 10,000 visits. No trend was found toward more frequent testing after adjustment for patient characteristics, risk factors, and provider characteristics (P = 0.134). Cardiac stress tests with imaging comprised a growing portion of all tests, increasing from 59% in 1993 to 1995 to 87% in 2008 to 2010. At least 34.6% were probably inappropriate, with associated annual costs and harms of $501 million and 491 future cases of cancer. Authors found no evidence of a lower likelihood of black patients receiving a cardiac stress test (odds ratio, 0.91 [95% CI, 0.69 to 1.21]) than white patients, although some evidence of disparity in Hispanic patients was found (odds ratio, 0.75 [CI, 0.55 to 1.02]). LIMITATION: Cross-sectional design with limited clinical data.

conclusionNational growth in cardiac stress test use can largely be explained by population and provider characteristics, but use of imaging cannot. Physician decision making about cardiac stress test use does not seem to contribute to racial/ethnic disparities in cardiovascular disease. PRIMARY FUNDING SOURCE: National Heart, Lung, and Blood Institute and the National Center for Advancing Translational Sciences.

Indexed as

AdolescentAdultAgedAged, 80 and overCardiac Imaging TechniquesCoronary DiseaseCross-Sectional StudiesDecision MakingDemographyEthnicityExercise TestHealth Care SurveysHumansMiddle AgedPractice Patterns, Physicians'Risk Factors

Identifiers

PMID25285541
PMCPMC4335355
OpenAlexW1977264459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.