Evidence map›Paper›PMID 25285123›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2014

From the mouth of babes: Getting vaccinated doesn't have to hurt.

Anna Taddio, Andrew F Ilersich, Anthony N Ilersich, Jenny Wells

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06004258 (Effectiveness of the Painless Vaccination Protocol Versus Traditional Vaccination Methodology in Reducing Pain in Children Aged 2 Months to 14 Years. A Multicenter, Quasi-experimental), which is not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06004258 nacompletednot on this mapstarted 2022, after this paper: background citation

Effectiveness of the Painless Vaccination Protocol Versus Traditional Vaccination Methodology in Reducing Pain in Children Aged 2 Months to 14 Years. A Multicenter, Quasi-experimental (Non-randomized) Controlled Study

TypeinterventionalSponsorHospital Universitario Virgen MacarenaRan2022 to 2023Enrolled495ConditionsPainArmsPainless Vaccination
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Reducing distress during vaccine injections: 2026 clinical practice guideline update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Guideline
  2. Pooled it
  3. Pooled it
  4. Reducing pain during vaccine injections: clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2015
    Guideline
  5. Article
  6. Article
  7. Managing pain and fear: Playing your CARDs to improve the vaccination experience.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
  8. Article
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  10. Children's rights as law in Sweden-every health-care encounter needs to meet the child's needs.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
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  13. Observational
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  19. Taking the sting out of school-based immunizations.Paediatrics & child health · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Anna TaddioClinical, Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, and Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario.
Andrew F IlersichClinical, Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, and Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario.
Anthony N IlersichClinical, Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, and Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario.
Jenny WellsAboutKidsHealth, The Hospital for Sick Children, Toronto, Ontario.
University of Toronto · CA3M (United States) · USSickKids Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnalgesic interventions are not commonly administered during childhood vaccination, despite the fact that two-thirds of children are afraid of needles and one-tenth are noncompliant with immunization.

objectiveTo explore children's experiences of vaccination and preferences for analgesia.

methodsA total of 17 children (four to 14 years of age) at an independent school in Toronto (Ontario) participated in three focus-group interviews. The majority had previous experience with pain management interventions during vaccination. Thematic content analysis was used to analyze interview transcripts.

resultsTHE FINDINGS WERE CATEGORIZED INTO THREE MAIN THEMES: experience of vaccination; roles and responsibilities regarding pain management; and impact of pain management. Children easily recalled previous vaccinations and discussed fear and distress experienced by themselves and others. Children believed that parents and immunizers should prepare them ahead of time and use interventions to manage and monitor pain. They also wanted adults to support their efforts to lead pain management. Children discussed benefits of managing pain, including reduced unnecessary suffering, improved vaccination experience, reduced risk of developing needle fears and reduced noncompliant behaviours. They were knowledgeable about strategies for reducing pain including distraction, topical anesthetics and injection techniques. They contrasted vaccination with and without pain management, and indicated a preference for pain management.

conclusionChildren reported that managing vaccination pain is important and that analgesic interventions should routinely be used. Incorporating pain management in the process of vaccination has the potential to improve children's experiences with vaccination and promote more positive attitudes and behaviours.

Indexed as

ChildrenPain managementSchool-based immunization clinicsVaccination

Identifiers

PMID25285123
PMCPMC4173939
OpenAlexW2237595254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.