Evidence map›Paper›PMID 25284224›Full record

ArticlePrenatal diagnosis2015

Electrophysiologic features of fetal ventricular aneurysms and diverticula.

Carli Peters, Annette Wacker-Gussmann, Janette F Strasburger, Bettina F Cuneo, Nina L Gotteiner, Mehemet Gulecyuz, Ronald T Wakai

Open access · greenAbstract read
In one paragraph

Article in Prenatal diagnosis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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  13. Diagnosis and treatment of fetal arrhythmia.American journal of perinatology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Carli PetersDepartment of Medical Physics, University of Wisconsin, Madison, WI, USA.
Annette Wacker-Gussmann
Janette F Strasburger
Bettina F Cuneo
Nina L Gotteiner
Mehemet Gulecyuz
Ronald T Wakai
University of Wisconsin–Madison · USAdvocate Children's Hospital · USChildren's Hospital Colorado · USChildren's Hospital of Wisconsin · USDeutsches Herzzentrum München · DELurie Children's Hospital · US

Funding

Optimized Signal Processing of Fetal MCG R01HL063174 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WAKAI, RONALD T · 1999 to 2020
$8.4M
NHLBI NIH HHS R01 HL063174NHLBI NIH HHS R01 HL63174
6 · The paper itself

Abstract

objectiveCongenital ventricular wall defects are very rare and include congenital ventricular aneurysms (CVAs) and diverticula (CVDs).

methodWe report a series of five fetuses: three with CVAs and two with CVDs referred due to fetal arrhythmia. In addition to routine fetal echocardiography, fetal magnetocardiography (fMCG) was used. The literature in CVA and CVD is reviewed.

resultsIncessant premature ventricular contractions (PVC), mainly bigeminy and trigeminy were found in three fetuses with CVAs and in one with CVD, who also had ventricular couplets. The other fetus with CVD, referred because of PVCs, had only sinus tachycardia. ST elevation was noted in two. Fetal movement had a variable impact on PVCs. Postnatal evaluation demonstrated two persistent left ventricular aneurysms and one persistent right CVD; one CVD resolved at 35-week gestation. Two neonates had incessant PVCs. Both arrhythmias resolved spontaneously while being treated with propranolol.

conclusionFMCG is complementary to echocardiographic imaging. In fetuses with left ventricular wall defects, additional electrophysiological diagnosis can be made by fMCG, including the complexity of ventricular ectopy, arrhythmic response to fetal movement, presence of ST-T wave abnormalities, and atrial amplitude increases. Prenatal risk factor assessment using fMCG can additionally support post-natal treatment and follow-up.

Indexed as

DiverticulumEchocardiographyFemaleFetal DiseasesFetal HeartHeart AneurysmHumansInfant, NewbornMagnetocardiographyPregnancyRetrospective Studies

Identifiers

PMID25284224
PMCPMC4319987
OpenAlexW1564552655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.