Evidence map›Paper›PMID 25283955›Full record

ArticleArthritis care & research2015

Sleep disturbance in osteoarthritis: linkages with pain, disability, and depressive symptoms.

Patricia A Parmelee, Caitlan A Tighe, Natalie D Dautovich

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthritis care & research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 8 pooled it
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 8 syntheses or guidelines pooled it, 226 citations in OpenAlex.

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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Patricia A ParmeleeUniversity of Alabama, Tuscaloosa.
Caitlan A Tighe
Natalie D Dautovich
University of Alabama · US

Funding

Everyday Quality of Life in Blacks and Whites with OsteoarthritisR01AG041655 · NIA · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI PARMELEE, PATRICIA A., SMITH, DYLAN MICHAEL · 2012 to 2016
$2.5M
DEPRESSION, DISABILITY AND PAIN IN OSTEOARTHRITISR01MH051800 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI PARMELEE, PATRICIA A. · 1994 to 1997
–
NIA NIH HHS R01 AG041655NIMH NIH HHS R01 MH051800
6 · The paper itself

Abstract

objectiveIt is known that osteoarthritis (OA) increases the risk of sleep disturbance, and that both pain and sleep problems may trigger functional disability and depression. However, studies examining all 4 variables simultaneously are rare. The aim of this study was to examine cross-sectional and longitudinal associations of self-reported sleep disturbance with OA-related pain and disability and depressive symptoms.

methodsAt baseline, 367 persons with physician-diagnosed knee OA reported sleep disturbances, pain, functional limitations, and depressive symptoms. At 1-year followup, all measures were repeated in 288 of the subjects. Baseline analyses examined the independent and interactive associations of sleep disturbance with pain, disability, and depression, net of demographics and general health. Longitudinal analyses used baseline sleep disturbance to predict the 1-year change in pain, disability, and depression.

resultsAt baseline, sleep was independently associated with pain and depression but not disability. The sleep-pain relationship was mediated by depressive symptoms; sleep interacted with pain to exacerbate depression among persons with high levels of pain. Baseline sleep disturbance predicted increased depression and disability, but not pain, at followup.

conclusionThese data confirm known cross-sectional relationships between sleep disturbance and pain and depression and provide new insights regarding longitudinal associations among those variables. Depression appears to play a strong role in the sleep-pain linkage, particularly when pain is severe. The unique predictive role of sleep in the progression of disability requires further study but may be an important point of intervention to prevent OA-related functional decline among persons whose sleep is disrupted by OA-related pain.

Indexed as

Disability EvaluationAgedAged, 80 and overArthralgiaCross-Sectional StudiesDepressionFemaleHumansLongitudinal StudiesMaleMiddle AgedOsteoarthritis, KneePain MeasurementPredictive Value of TestsRisk FactorsSleep Wake Disorders

Identifiers

PMID25283955
PMCPMC4342277
OpenAlexW2111079817

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.