Evidence map›Paper›PMID 25283500›Full record

ArticleInternational journal of clinical practice2015

Development of UK guidance on the management of erectile dysfunction resulting from radical radiotherapy and androgen deprivation therapy for prostate cancer.

I D White, J Wilson, P Aslet, A B Baxter, A Birtle, B Challacombe, J Coe, L Grover, H Payne, S Russell and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Prevalence of erectile dysfunction in male survivors of cancer: a systematic review and meta-analysis of cross-sectional studies.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

I D WhiteUrology Unit, The Royal Marsden NHS Foundation Trust, London & Sutton, UK.
J Wilson
P Aslet
A B Baxter
A Birtle
B Challacombe
J Coe
L Grover
H Payne
S Russell
V Sangar
N Van As
M Kirby
Royal Marsden NHS Foundation Trust · GBAddenbrooke's Hospital · GBGuy's Hospital · GBHampshire Hospitals NHS Foundation Trust · GBLondon Clinic · GBThe Christie NHS Foundation Trust · GBThe Prostate Centre · GBUniversity College Hospital · GBUniversity College London · GBUniversity of Manchester · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo develop a management strategy (rehabilitation programme) for erectile dysfunction (ED) after radiotherapy (RT) or androgen deprivation therapy (ADT) for prostate cancer that is suitable for use in a UK NHS healthcare context.

methodsPubMed literature searches of ED management in this patient group together with a survey of 28 experts in the management of treatment-induced ED from across the UK were conducted.

resultsData from 19 articles and completed questionnaires were collated. The findings discussed in this article confirm that RT/ADT for prostate cancer can significantly impair erectile function. While many men achieve erections through PDE5-I use, others need combined management incorporating exercise and lifestyle modifications, psychosexual counselling and other erectile aids. This article offers a comprehensive treatment algorithm to manage patients with ED associated with RT/ADT.

conclusionBased on published research literature and survey analysis, recommendations are proposed for the standardisation of management strategies employed for ED after RT/ADT. In addition to implementing the algorithm, understanding the rationale for the type and timing of ED management strategies is crucial for clinicians, men and their partners.

Indexed as

Practice Guidelines as TopicAndrogen AntagonistsAntineoplastic Agents, HormonalErectile DysfunctionHumansMaleProstatic NeoplasmsQuality of LifeRadiotherapyUnited KingdomAndrogen AntagonistsAntineoplastic Agents, Hormonal

Identifiers

PMID25283500
PMCPMC4309408
OpenAlexW2038819569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.