ArticleMicrovascular research2015
Segmentation and quantification of blood vessels for OCT-based micro-angiograms using hybrid shape/intensity compounding.
Article in Microvascular research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- VesSynth: Tubes Are All You Need for Robust Cross-Scale Cross-Modal 3D Vessel Segmentation.bioRxiv : the preprint server for biology · 2026Article
- 3D reconstruction of human liver tissue at cellular resolution.Science advances · 2026Article
- Large Scale in vivo Acquisition, Segmentation and 3D Reconstruction of Cortical Vasculature usingNeuroinformatics · 2025Article
- Quantitative Optimization of Handheld Probe External Pressure on Dermatological Microvasculature Using Optical Coherence Tomography-Based Angiography.Micromachines · 2024Article
- Impairment of cerebral vascular reactivity and resting blood flow in early-staged transgenic AD mice:Research square · 2023Article
- Microsurgery Robots: Applications, Design, and Development.Sensors (Basel, Switzerland) · 2023Review
- A retinal imaging system for combined measurement of optic nerve head vascular pulsation and stimulated vasodilation in humans.Scientific reports · 2023Article
- Sex Difference in Capillary Reperfusion After Transient Middle Cerebral Artery Occlusion in Diabetic Mice.Stroke · 2023Article
- [Effects and mechanism of human umbilical vein endothelial cells-derived exosomes on wound healing in diabetic rabbits].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Highly accurate, automated quantification of 2D/3D orientation for cerebrovasculature using window optimizing method.Journal of biomedical optics · 2022Article
- Blood vessel tail artifacts suppression in optical coherence tomography angiography.Neurophotonics · 2022Article
- Segmentation-Less, Automated, Vascular Vectorization.PLoS computational biology · 2021Article
- Past, present and future role of retinal imaging in neurodegenerative disease.Progress in retinal and eye research · 2021Review
- An optimized segmentation and quantification approach in microvascular imaging for OCTA-based neovascular regression monitoring.BMC medical imaging · 2021Observational
- Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography.Progress in retinal and eye research · 2021Review
- Full three-dimensional segmentation and quantification of tumor vessels for photoacoustic images.Photoacoustics · 2020Article
- Automated vessel diameter quantification and vessel tracing for OCT angiography.Journal of biophotonics · 2020Article
- In vivo detection of tumor boundary using ultrahigh-resolution optical coherence angiography and fluorescence imaging.Journal of biophotonics · 2020Article
- Quantification of Morphological Features in Non-Contrast-Enhanced Ultrasound Microvasculature Imaging.IEEE access : practical innovations, open solutions · 2020Article
- Automated segmentation and quantification of OCT angiography for tracking angiogenesis progression.Biomedical optics express · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Optical coherence tomography (OCT) based microangiography is capable of visualizing 3D functional blood vessel networks within microcirculatory tissue beds in vivo. To provide the quantitative information of vasculature from the microangiograms such as vessel diameter and morphology, it is necessary to develop efficient vessel segmentation algorithms. In this paper, we propose to develop a hybrid Hessian/intensity based method to segment and quantify shape and diameter of the blood vessels innervating capillary beds that are imaged by functional OCT in vivo. The proposed method utilizes multi-scale Hessian filters to segment tubular structures such as blood vessels, but compounded by the intensity-based segmentation method to mitigate the limitations of Hessian filters' sensitivity to the selection of scale parameters. Such compounding segmentation scheme takes advantage of the morphological nature of Hessian filters while correcting for the scale parameter selection by intensity-based segmentation. The proposed algorithm is tested on a wound healing model and its performance of segmentation vessels is quantified by a publicly available manual segmentation dataset. We believe that this method will play an important role in the quantification of micro-angiograms for microcirculation research in ophthalmology and diagnosing retinal eye diseases involved with microcirculation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.