Evidence map›Paper›PMID 25283184›Full record

ReviewCurrent HIV/AIDS reports2014

Role of oral pre-exposure prophylaxis (PrEP) in current and future HIV prevention strategies.

David N Burns, Cynthia Grossman, Jim Turpin, Vanessa Elharrar, Fulvia Veronese

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Belief in Treatment as Prevention and Its Relationship to HIV Status and Behavioral Risk.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  14. Article
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  16. Editorial Commentary: Keeping Our Eyes on the Prize: No New HIV Infections With Increased Use of HIV Pre-exposure Prophylaxis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David N BurnsDivision of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 5601 Fishers Lane, MSC 9831, Bethesda, MD, 20892, USA, burnsda@niaid.nih.gov.
Cynthia Grossman
Jim Turpin
Vanessa Elharrar
Fulvia Veronese
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment as prevention is expected to have a major role in reducing HIV incidence, but other prevention interventions will also be required to bring the epidemic under control, particularly among key populations. One or more forms of pre-exposure prophylaxis (PrEP) will likely play a critical role. Oral PrEP with emtricitabine-tenofovir (Truvada®) is currently available in the US and some other countries, but uptake has been slow. We review the concerns that have contributed to this slow uptake and discuss current and future research in this critical area of HIV prevention research.

Indexed as

Administration, OralAnti-Retroviral AgentsDeoxycytidineDrug CombinationsEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationFemaleHIV InfectionsHumansMaleOrganophosphorus CompoundsPre-Exposure ProphylaxisAnti-Retroviral AgentsDeoxycytidineDrug CombinationsEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationOrganophosphorus Compounds

Identifiers

PMID25283184
OpenAlexW2086565471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.