ArticleBMC genomics2014
Functional genomics of acclimation and adaptation in response to thermal stress in Daphnia.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed, 92 citations in OpenAlex.
- Mild Warming Induces Divergent Plastic Responses in Gene Expression Among Populations of a Temperate Butterfly.Molecular ecology · 2026Article
- Delayed transcriptional response of Daphnia pulex to thermal stress.G3 (Bethesda, Md.) · 2026Article
- The effects of multi-generational exposure to Fluorine-Free Foam (F3) alternatives on Daphnia magna tolerance.Ecotoxicology (London, England) · 2025Article
- Asymmetric Micro-Evolutionary Responses in a Warming World: Heat-Driven Adaptation Enhances Metal Tolerance in a Planktonic Rotifer, but Not Vice Versa.Global change biology · 2025Article
- Environmental transcriptomics under heat stress: Can environmental RNA reveal changes in gene expression of aquatic organisms?Molecular ecology · 2025Article
- Experimental ecology and the balance between realism and feasibility in aquatic ecosystems.Nature communications · 2025Review
- The relative impact of parental and current environment on plant transcriptomes depends on type of stress and genotype.Proceedings. Biological sciences · 2023Article
- Diet effects on longevity, heat tolerance, lipid peroxidation and mitochondrial membrane potential in Daphnia.Oecologia · 2023Article
- Transcriptome wide analyses reveal intraspecific diversity in thermal stress responses of a dominant habitat-forming species.Scientific reports · 2023Article
- Genome Assembly of a Relict Arabian Species ofInternational journal of molecular sciences · 2023Article
- The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia.Ecology and evolution · 2022Article
- Gene expression underlying parenting and being parented shows limited plasticity in response to different ambient temperatures.Molecular ecology · 2022Article
- Article
- Population-Genomic Analysis Identifies a Low Rate of Global Adaptive Fixation in the Proteins of the Cyclical Parthenogen Daphnia magna.Molecular biology and evolution · 2022Article
- Phenotypic and transcriptional response of Daphnia pulicaria to the combined effects of temperature and predation.PloS one · 2022Article
- Thermal stress and mutation accumulation increase heat shock protein expression inEvolutionary ecology · 2022Article
- Balancing Selection for Pathogen Resistance Reveals an Intercontinental Signature of Red Queen Coevolution.Molecular biology and evolution · 2021Article
- Mitochondrial volume density and evidence for its role in adaptive divergence in response to thermal tolerance in threespine stickleback.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
- Article
- A comprehensive epigenomic analysis of phenotypically distinguishable, genetically identical female and male Daphnia pulex.BMC genomics · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundGene expression regulation is one of the fundamental mechanisms of phenotypic plasticity and is expected to respond to selection in conditions favoring phenotypic response. The observation that many organisms increase their stress tolerance after acclimation to moderate levels of stress is an example of plasticity which has been long hypothesized to be based on adaptive changes in gene expression. We report genome-wide patterns of gene expression in two heat-tolerant and two heat-sensitive parthenogenetic clones of the zooplankton crustacean Daphnia pulex exposed for three generations to either optimal (18°C) or substressful (28°C) temperature.
resultsA large number of genes responded to temperature and many demonstrated a significant genotype-by-environment (GxE) interaction. Among genes with a significant GxE there were approximately equally frequent instances of canalization, i.e. stronger plasticity in heat-sensitive than in heat-tolerant clones, and of enhancement of plasticity along the evolutionary vector toward heat tolerance. The strongest response observed is the across-the-board down-regulation of a variety of genes occurring in heat-tolerant, but not in heat-sensitive clones. This response is particularly obvious among genes involved in core metabolic pathways and those responsible for transcription, translation and DNA repair.
conclusionsThe observed down-regulation of metabolism, consistent with previous findings in yeast and Drosophila, may reflect a general compensatory stress response. The associated down-regulation of DNA repair pathways potentially creates a trade-off between short-term benefits of survival at high temperature and long-term costs of accelerated mutation accumulation.
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