Evidence map›Paper›PMID 25282308›Full record

ArticleDrug and alcohol dependence2014

Factors associated with initiating someone into illicit drug injection.

Ricky N Bluthenthal, Lynn Wenger, Daniel Chu, Brendan Quinn, James Thing, Alex H Kral

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Substance use & misuse · 2019
    Article
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  19. Non-injection Drug Use and Injection Initiation Assistance among People Who Inject Drugs in Tijuana, Mexico.Journal of urban health : bulletin of the New York Academy of Medicine · 2018
    Article
  20. Preventing Injection Drug use Initiation: State of the Evidence and Opportunities for the Future.Journal of urban health : bulletin of the New York Academy of Medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ricky N BluthenthalDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California Soto Street Building, SSB 2001 N. Soto Street, MC 9239, Los Angeles, CA 90033, USA. Electronic address: rbluthen@usc.edu.
Lynn WengerUrban Health Program, RTI International, 351 California St., San Francisco, CA 94104, USA.
Daniel ChuDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California Soto Street Building, SSB 2001 N. Soto Street, MC 9239, Los Angeles, CA 90033, USA.
Brendan QuinnCentre for Population Health, Burnet Institute, 85 Commercial Rd., Melbourne, VIC 3004, Australia.
James ThingDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California Soto Street Building, SSB 2001 N. Soto Street, MC 9239, Los Angeles, CA 90033, USA.
Alex H KralUrban Health Program, RTI International, 351 California St., San Francisco, CA 94104, USA.

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Saul Priceman · 1985 to 2026
$181.4M
Training grant for Cancer Control and EpidemiologyT32CA009492 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN · 1985 to 2019
$7.4M
Exploratory Research on Late Initiation of Drug InjectionR01DA027689 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BLUTHENTHAL, RICKY N, KRAL, ALEXANDER H · 2010 to 2012
$1.7M
NCI NIH HHS P30 CA014089NCI NIH HHS P30CA014089NCI NIH HHS T32 CA009492NIDA NIH HHS R01 DA027689NIDA NIH HHS R01DA027689
6 · The paper itself

Abstract

aimsMost people who inject drugs (PWID) were first initiated into injection by a current PWID. Few studies have examined PWID who assist others into drug injection. Our goal is to describe the prevalence of and risk factors for initiating someone into injection in the last 12 months.

methodsWe recruited a cross-sectional sample of PWID (N=605) in California from 2011 to 2013. We examined bivariate and multivariate risk factors for initiating someone into injection with a focus on behaviors that might encourage injection initiation such as injecting in front of non-PWID, describing how to inject to non-PWID, and willingness to initiate someone into drug injection.

resultsHaving initiated someone into injection was reported by 34% of PWID overall and 7% in the last 12 months. Forty-four PWID had assisted 431 people into injection in the past year. Factors independently associated with initiating someone into injection in the last 12 months were self-reported likelihood of initiating someone in the future (Adjusted Odds Ratio [AOR]=7.09; 95% Confidence Interval [CI]=3.40, 14.79), having injected another PWID in past month (AOR=4.05; 95% confidence interval [CI]=1.94, 8.47), having described how to inject to non-injectors (2.61; 95% CI=1.19, 5.71), and non-injection powder cocaine use in past month (AOR=4.97; 95% CI=2.08, 11.84) while controlling for study site.

conclusionActive PWID are important in facilitating the process of drug injection uptake. Interventions to reduce initiation should include efforts to change behaviors and intentions among PWID that are associated with injection uptake among others.

Indexed as

AdultBehavior, AddictiveCaliforniaCross-Sectional StudiesFemaleHumansIllicit DrugsInjectionsMaleMiddle AgedOdds RatioPrevalenceRisk FactorsSubstance Abuse, IntravenousIllicit DrugsHIV/HCVInitiatorsInjection drug useInjection initiationObservational epidemiologyPWID

Identifiers

PMID25282308
PMCPMC4276720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.