ArticleCortex; a journal devoted to the study of the nervous system and behavior2015
A dissociation between stopping and switching actions following a lesion of the pre-supplementary motor area.
Article in Cortex; a journal devoted to the study of the nervous system and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of cue transparency in task switching: an SDM-PSI meta-analysis in healthy adults.Brain imaging and behavior · 2026Pooled it
- A cortico-subthalamic circuit rapidly engages and releases inhibition of specific movements depending on the environmental context.PLoS biology · 2026Article
- Cortico-basal ganglia dynamics of global and selective response inhibition in humans.bioRxiv : the preprint server for biology · 2026Article
- Altered Effective Connectivity of the Numerical Brain in Children With Developmental Dyscalculia.Journal of neuroscience research · 2025Article
- Common and Unique Neurophysiological Processes That Support the Stopping and Revising of Actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Causal computations of supplementary motor area on spatial impulsivity.Scientific reports · 2024Article
- The Differentiation of Self-Motion From External Motion Is a Prerequisite for Postural Control: A Narrative Review of Visual-Vestibular Interaction.Frontiers in human neuroscience · 2022Review
- Towards real-world generalizability of a circuit for action-stopping.Nature reviews. Neuroscience · 2021Review
- Effects of galvanic vestibular stimulation on resting state brain activity in patients with bilateral vestibulopathy.Human brain mapping · 2020Article
- An fMRI study of inhibitory control and the effects of exposure to violence in Latin-American early adolescents: alterations in frontoparietal activation and performance.Social cognitive and affective neuroscience · 2019Article
- Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition.PloS one · 2019Article
- Brain Activation of Elite Race Walkers in Action Observation, Motor Imagery, and Motor Execution Tasks: A Pilot Study.Frontiers in human neuroscience · 2019Article
- Transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder: current perspectives.Neuropsychiatric disease and treatment · 2018Review
- Subthalamic nucleus stimulation impairs emotional conflict adaptation in Parkinson's disease.Social cognitive and affective neuroscience · 2017Article
- Functional neuroimaging of visuo-vestibular interaction.Brain structure & function · 2017Article
- A dual but asymmetric role of the dorsal anterior cingulate cortex in response inhibition and switching from a non-salient to salient action.NeuroImage · 2016Article
- Time-Perception Network and Default Mode Network Are Associated with Temporal Prediction in a Periodic Motion Task.Frontiers in human neuroscience · 2016Article
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Authors and funding
2 authors.
Funding
Abstract
introductionAlthough the pre-supplementary motor area (pre-SMA) is one of the most frequently reported areas of activation in functional imaging studies, the role of this brain region in cognition is still a matter of intense debate. Here we present a patient with a focal lesion of caudal pre-SMA who displays a selective deficit in updating a response plan to switch actions, but shows no impairment when required to withhold a response - stopping. MATERIALS &
methodsThe patient and a control group underwent three tasks designed to measure different aspects of cognitive control and executive function.
resultsThe pre-SMA patient displayed no impairment when responding in the face of distracting stimuli (Eriksen flanker paradigm), or when required to halt an on-going response (STOP task). However, a specific deficit was observed when she was required to rapidly switch between response plans (CHANGE task).
conclusionsThese findings suggest that the caudal pre-SMA may have a particularly important role in a network of brain regions required for rapidly updating and implementing response plans. The lack of any significant impairment on other measures of cognitive control suggests that this is not likely due to a global deficit in cognitive control. We discuss the implications of these results in the context of current theories of pre-SMA function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.