ArticleMedical physics2014
Cascaded systems analysis of photon counting detectors.
Article in Medical physics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Development of a customizable model for spectral photon-counting detector CT.Medical physics · 2025Article
- Framework for evaluating photon-counting detectors under pile-up conditions.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- A framework to model charge sharing and pulse pileup for virtual imaging trials of photon-counting CT.Physics in medicine and biology · 2024Article
- Development and validation of a noise insertion algorithm for photon-counting-detector CT.Medical physics · 2024Article
- Noise power spectrum (NPS) in computed tomography: Enabling local NPS measurement without stationarity and ergodicity assumptions.Medical physics · 2024Article
- Method of determining technique from weight and height to achieve targeted detector exposures in portable chest and abdominal digital radiography.Journal of applied clinical medical physics · 2022Article
- Spectral Photon Counting CT: Imaging Algorithms and Performance Assessment.IEEE transactions on radiation and plasma medical sciences · 2021Article
- Anomalous edge response of cadmium telluride-based photon counting detectors jointly caused by high-flux radiation and inter-pixel communication.Physics in medicine and biology · 2021Article
- Detective quantum efficiency of photon-counting CdTe and Si detectors for computed tomography: a simulation study.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- Frequency-dependent signal and noise in spectroscopic x-ray imaging.Medical physics · 2020Article
- Task-driven optimization of the non-spectral mode of photon counting CT for intracranial hemorrhage assessment.Physics in medicine and biology · 2019Article
- Resolution characterization of a silicon-based, photon-counting computed tomography prototype capable of patient scanning.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- Impacts of photon counting CT to maximum intensity projection (MIP) images of cerebral CT angiography: theoretical and experimental studies.Physics in medicine and biology · 2019Article
- An experimental method to directly measure DQE[Formula: see text] at k = 0 for 2D x-ray imaging systems.Physics in medicine and biology · 2019Article
- A framework for performance characterization of energy-resolving photon-counting detectors.Medical physics · 2018Article
- Impact of anti-charge sharing on the zero-frequency detective quantum efficiency of CdTe-based photon counting detector system: cascaded systems analysis and experimental validation.Physics in medicine and biology · 2018Article
- Feasibility of Dose-reduced Chest CT with Photon-counting Detectors: Initial Results in Humans.Radiology · 2017Article
- Energy-sensitive photon counting detector-based X-ray computed tomography.Radiological physics and technology · 2017Review
- Signal and noise characteristics of a CdTe-based photon counting detector: Cascaded systems analysis and experimental studies.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
- Technical Note: spektr 3.0-A computational tool for x-ray spectrum modeling and analysis.Medical physics · 2016Article
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9 authors.
Funding
Abstract
purposePhoton counting detectors (PCDs) are an emerging technology with applications in spectral and low-dose radiographic and tomographic imaging. This paper develops an analytical model of PCD imaging performance, including the system gain, modulation transfer function (MTF), noise-power spectrum (NPS), and detective quantum efficiency (DQE).
methodsA cascaded systems analysis model describing the propagation of quanta through the imaging chain was developed. The model was validated in comparison to the physical performance of a silicon-strip PCD implemented on an experimental imaging bench. The signal response, MTF, and NPS were measured and compared to theory as a function of exposure conditions (70 kVp, 1-7 mA), detector threshold, and readout mode (i.e., the option for coincidence detection). The model sheds new light on the dependence of spatial resolution, charge sharing, and additive noise effects on threshold selection and was used to investigate the factors governing PCD performance, including the fundamental advantages and limitations of PCDs in comparison to energy-integrating detectors (EIDs) in the linear regime for which pulse pileup can be ignored.
resultsThe detector exhibited highly linear mean signal response across the system operating range and agreed well with theoretical prediction, as did the system MTF and NPS. The DQE analyzed as a function of kilovolt (peak), exposure, detector threshold, and readout mode revealed important considerations for system optimization. The model also demonstrated the important implications of false counts from both additive electronic noise and charge sharing and highlighted the system design and operational parameters that most affect detector performance in the presence of such factors: for example, increasing the detector threshold from 0 to 100 (arbitrary units of pulse height threshold roughly equivalent to 0.5 and 6 keV energy threshold, respectively), increased the f50 (spatial-frequency at which the MTF falls to a value of 0.50) by ∼30% with corresponding improvement in DQE. The range in exposure and additive noise for which PCDs yield intrinsically higher DQE was quantified, showing performance advantages under conditions of very low-dose, high additive noise, and high fidelity rejection of coincident photons.
conclusionsThe model for PCD signal and noise performance agreed with measurements of detector signal, MTF, and NPS and provided a useful basis for understanding complex dependencies in PCD imaging performance and the potential advantages (and disadvantages) in comparison to EIDs as well as an important guide to task-based optimization in developing new PCD imaging systems.
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