Evidence map›Paper›PMID 25281800›Full record

ArticleNeuroImage2015

Resting-state networks predict individual differences in common and specific aspects of executive function.

Andrew E Reineberg, Jessica R Andrews-Hanna, Brendan E Depue, Naomi P Friedman, Marie T Banich

Registry-linked trialAbstract read
In one paragraph

Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07479966 (Resting-state Connectivity and Individual Differences in Affective Placebo Responsiveness), which is not on this map. Cited by 117 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07479966 enrolling by invitationnot on this mapstarted 2022, after this paper: background citation

Resting-state Connectivity and Individual Differences in Affective Placebo Responsiveness

TypeobservationalSponsorStefanie BrassenRan2022 to 2026Enrolled50ConditionsCondition: HealthyArmsNo intervention
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  8. Resting-state functional connectivity and cognitive impairment after COVID-19 infection: Evidence from a large-scale fMRI study.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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  20. Prenatal chronic inflammation and children's executive function development.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025
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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew E ReinebergDepartment of Psychology and Neuroscience, University of Colorado Boulder, Muenzinger D244, 345 UCB, Boulder, CO 80309-034, USA. Electronic address: andrew.reineberg@colorado.edu.
Jessica R Andrews-HannaInstitute of Cognitive Science, University of Colorado Boulder, 344 UCB, Boulder, CO 80309-0344, USA.
Brendan E DepueDepartment of Psychology and Neuroscience, University of Colorado Boulder, Muenzinger D244, 345 UCB, Boulder, CO 80309-034, USA; Institute of Cognitive Science, University of Colorado Boulder, 344 UCB, Boulder, CO 80309-0344, USA.
Naomi P FriedmanDepartment of Psychology and Neuroscience, University of Colorado Boulder, Muenzinger D244, 345 UCB, Boulder, CO 80309-034, USA; Institute for Behavioral Genetics, University of Colorado Boulder, 1480 30th St., Boulder, CO 80303, USA.
Marie T BanichDepartment of Psychology and Neuroscience, University of Colorado Boulder, Muenzinger D244, 345 UCB, Boulder, CO 80309-034, USA; Institute of Cognitive Science, University of Colorado Boulder, 344 UCB, Boulder, CO 80309-0344, USA.

Funding

Proj 5: Early Development (224-250)P50MH079485 · NIMH · UNIVERSITY OF COLORADO · PI O'REILLY, RANDALL CHARLES · 2008 to 2012
$8.7M
NIMH NIH HHS P50 MH079485
6 · The paper itself

Abstract

The goal of the present study was to examine relationships between individual differences in resting state functional connectivity as ascertained by fMRI (rs-fcMRI) and performance on tasks of executive function (EF), broadly defined as the ability to regulate thoughts and actions. Unlike most previous research that focused on the relationship between rs-fcMRI and a single behavioral measure of EF, in the current study we examined the relationship of rs-fcMRI with individual differences in subcomponents of EF. Ninety-one adults completed a resting state fMRI scan and three separate EF tasks outside the magnet: inhibition of prepotent responses, task set shifting, and working memory updating. From these three measures, we derived estimates of common aspects of EF, as well as abilities specific to working memory updating and task shifting. Using Independent Components Analysis (ICA), we identified across the group of participants several networks of regions (Resting State Networks, RSNs) with temporally correlated time courses. We then used dual regression to explore how these RSNs covaried with individual differences in EF. Dual regression revealed that increased higher common EF was associated with connectivity of a) frontal pole with an attentional RSN, and b) Crus I and II of the cerebellum with the right frontoparietal RSN. Moreover, higher shifting-specific abilities were associated with increased connectivity of angular gyrus with a ventral attention RSN. The results of the current study suggest that the organization of the brain at rest may have important implications for individual differences in EF, and that individuals higher in EF may have expanded resting state networks as compared to individuals with lower EF.

Indexed as

IndividualityAdolescentAdultCerebellumExecutive FunctionFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemory, Short-TermNerve NetPredictive Value of TestsPrincipal Component AnalysisPsychomotor PerformanceSaccadesBehaviorExecutive controlICAIndividual differencesrs-fcMRI

Identifiers

PMID25281800
PMCPMC4262251

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.