Evidence map›Paper›PMID 25281364›Full record

ArticleAmerican journal of obstetrics and gynecology2015

Postpartum care for mothers diagnosed with hepatitis B during pregnancy.

Matthew S Chang, Ruth Tuomala, Anna E Rutherford, Muthoka L Mutinga, Karin L Andersson, Blaire E Burman, Robert S Brown, Emily Oken, Chinweike Ukomadu

Open access · greenAbstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. [APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Matthew S ChangDivision of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address: mchang5@partners.org.
Ruth TuomalaDepartment of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA.
Anna E RutherfordDivision of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA.
Muthoka L MutingaDivision of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA.
Karin L AnderssonDivision of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA.
Blaire E BurmanDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA.
Robert S BrownCenter for Liver Disease and Transplantation, College of Physicians and Surgeons, Columbia University, New York, NY.
Emily OkenDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.
Chinweike UkomaduDivision of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA.
Brigham and Women's Hospital · USColumbia University · USHarvard Pilgrim Health Care · USMassachusetts General Hospital · USUniversity of California, San Francisco · US

Funding

NRSA Hepatology Training GrantT32DK060414 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mandana Khalili, JACQUELYN J. MAHER · 2002 to 2026
$6.8M
Patient-oriented Research in Maternal Perinatal Overnutrition and Child AdiposityK24HD069408 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2011 to 2015
$844k
NICHD NIH HHS K24 HD069408NIDDK NIH HHS T32 DK060414
6 · The paper itself

Abstract

objectiveWe sought to determine rates of maternal postpartum hepatitis B virus (HBV) follow-up with a HBV specialist and identify factors associated with poor follow-up, as prior research has focused on infant outcomes and not maternal care. STUDY

designWe conducted a retrospective review of data from Partners HealthCare system, the largest health care system in Massachusetts, and identified women with chronic HBV who delivered from 2002 through 2012.

resultsWe identified 291 women (mean age 31.5 years, 51% Asian) with incident HBV during pregnancy. In all, 47% had postpartum follow-up with a HBV specialist, but only 19% also had appropriate laboratory tests (hepatitis B e antigen [HBeAg], hepatitis B e antibody, HBV DNA, and ALT) within 1 year of their HBV diagnosis. Mothers with HBV follow-up were more likely to have a primary care physician (PCP) within the Partners HealthCare system (66% vs 38%, P < .0001), a positive HBeAg (20% vs 8%, P = .004), and elevated AST values (17% vs 8%, P = .02). On multivariable logistic regression analysis, a mother who had a PCP (odds ratio, 2.50; 95% confidence interval, 1.37-4.59) or positive HBeAg (odds ratio, 4.45; 95% confidence interval, 1.64-12.06) had a greater likelihood of having HBV follow-up.

conclusionOnly 19% of HBV-infected mothers met care guidelines 1 year after being diagnosed with HBV. Inadequate postpartum HBV care affects women of all races/ethnicities. Women who had a PCP as well as those who were HBeAg positive were more likely to be referred for postpartum follow-up with a HBV specialist, suggesting that providers might be referring patients when they perceive HBV to be more serious or complex.

Indexed as

Academic Medical CentersAdultFemaleFollow-Up StudiesGastroenterologyHepatitis B, ChronicHumansLogistic ModelsMassachusettsMultivariate AnalysisPatient Acceptance of Health CarePostnatal CarePregnancyPregnancy Complications, InfectiousPrimary Health CareReferral and Consultationadherencecomplianceguidelinesprophylaxis

Identifiers

PMID25281364
PMCPMC4346392
OpenAlexW2060844049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.