ArticleDrug and alcohol dependence2014
Depressive symptoms, negative urgency and substance use initiation in adolescents.
Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 84 citations in OpenAlex.
- Transitions in Depressive Symptom Profiles Among Adolescents with Persistent Bullying Victimization: A Latent Transition Analysis.Behavioral sciences (Basel, Switzerland) · 2026Article
- A Multi-Method Meta-Analysis of Neuro-Behavioral Motor Inhibition Outcomes Across Substance-Use Problems and Related Developmental Psychopathological Conditions: A Self-Regulation Approach.Clinical neuropsychiatry · 2026Article
- Developmental relations between internalizing symptoms and negative urgency during middle adolescence.Development and psychopathology · 2026Article
- The causal interplay between depression and alcohol use from adolescence to young adulthood: a Mendelian randomization study.Psychological medicine · 2026Article
- The moderating role of trait impulsivity on reward sensitivity and alcohol craving.Addictive behaviors · 2025Article
- Adolescent Polysubstance Use and Co-Occurring Weapon Carrying, Bullying Victimization, and Depressive Symptomology: Patterns and Differences in the United States.Child psychiatry and human development · 2025Article
- Use of cannabis to manage symptoms of mental and physical health conditions during pregnancy: analysis of a pro-cannabis pregnancy forum.Frontiers in psychiatry · 2024Article
- Urgency as a predictor of change in emotion dysregulation in adolescents.Frontiers in psychiatry · 2024Article
- Pain and alcohol consumption in virtual reality.Experimental and clinical psychopharmacology · 2023Article
- Religious affiliation protects against alcohol/substance use initiation: A prospective study among healthy adolescents.Journal of adolescence · 2023Article
- Impulsivity and Reactive-Proactive Aggression as Mechanisms of Alcohol-Related Sexual Intimate Partner Violence Perpetration among Romantic Partners.Substance use & misuse · 2023Article
- The Genetically Informed Neurobiology of Addiction (GINA) model.Nature reviews. Neuroscience · 2023Review
- Investigating Microtemporal Processes Underlying Health Behavior Adoption and Maintenance: Protocol for an Intensive Longitudinal Observational Study.JMIR research protocols · 2022Article
- The role of affective urgency and emotion regulation in vaping susceptibility.Addictive behaviors reports · 2021Article
- CANUE: A Theoretical Model of Pain as an Antecedent for Substance Use.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Review
- Early-life stress affects drug abuse susceptibility in adolescent rat model independently of depression vulnerability.Scientific reports · 2020Article
- Longitudinal associations between negative urgency, symptoms of depression, cannabis and alcohol use in veterans.Experimental and clinical psychopharmacology · 2020Article
- Impulsive Responses to Positive and Negative Emotions: Parallel Neurocognitive Correlates and Their Implications.Biological psychiatry · 2020Review
- Greater delay discounting and cannabis coping motives are associated with more frequent cannabis use in a large sample of adult cannabis users.Drug and alcohol dependence · 2020Article
- Problematic Internet Use, Non-Medical Use of Prescription Drugs, and Depressive Symptoms among Adolescents: A Large-Scale Study in China.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundStudies show depressive symptoms are associated with substance use in adolescents, but the mechanism underlying this association is still unclear. This study investigated negative urgency - the disposition to rash action during emotional states - as a factor explaining relations between depressive symptoms and use of several substances.
methodsIn this cross-sectional study, 476 adolescents (mean age 14.5 years) completed self-report surveys. Regression models and products of coefficient analyses examined the overall relation of depressive symptoms to substance use and negative urgency as a statistical mediator of this association.
resultsDepression levels associated with increased likelihood of lifetime use of cigarettes, other forms of tobacco, marijuana, alcohol, inhalants, prescription painkillers, and any substance. Relations between depression levels and lifetime use of alcohol, inhalants, and any substance were accounted for (i.e., statistically mediated) by negative urgency. In adolescents endorsing lifetime use, depression levels associated with younger age of first use of other forms of tobacco and alcohol as well as use frequency of cigarette, alcohol, and composite frequency. Negative urgency accounted for the covariance between depression level and age of first use of alcohol, but did not for other forms of tobacco or frequency of use of any substances.
conclusionsDepression levels are associated with lifetime use of a variety of substances in early adolescence and targeting this risk factor with preventive efforts may be useful in reducing risk. Negative urgency may be an important target for interventions aimed at alcohol and inhalant use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.