Evidence map›Paper›PMID 25280495›Full record

ReviewClinical journal of the American Society of Nephrology : CJASN2015

Chemical and Physical Sensors in the Regulation of Renal Function.

Jennifer L Pluznick, Michael J Caplan

Abstract readReview
In one paragraph

Review in Clinical journal of the American Society of Nephrology : CJASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer L PluznickDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Michael J CaplanDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut michael.caplan@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to assess the status of the volume and composition of the body fluid compartment, the kidney monitors a wide variety of chemical and physical parameters. It has recently become clear that the kidney's sensory capacity extends well beyond its ability to sense ion concentrations in the forming urine. The kidney also keeps track of organic metabolites derived from a surprising variety of sources and uses a complex interplay of physical and chemical sensing mechanisms to measure the rate of fluid flow in the nephron. Recent research has provided new insights into the nature of these sensory mechanisms and their relevance to renal function.

Indexed as

Adenylyl CyclasesAnimalsBicarbonatesChemoreceptor CellsCiliaFatty Acids, VolatileHumansKidneyMechanoreceptorsSuccinic Acidadenylate cyclase 3Adenylyl CyclasesBicarbonatesFatty Acids, VolatileSuccinic Acidcell and transport physiologycell signalingrenal physiology

Identifiers

PMID25280495
PMCPMC4559500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.