Evidence map›Paper›PMID 25280245›Full record

ArticleAddictive behaviors2015

Causal pathways between impulsiveness, cocaine use consequences, and depression.

Jamey J Lister, David M Ledgerwood, Leslie H Lundahl, Mark K Greenwald

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jamey J ListerDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA. Electronic address: jlister@med.wayne.edu.
David M LedgerwoodDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA. Electronic address: dledgerwood@med.wayne.edu.
Leslie H LundahlDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA. Electronic address: llundahl@med.wayne.edu.
Mark K GreenwaldDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA; Department of Pharmacy Practice, Wayne State University, Detroit, MI, USA. Electronic address: mgreen@med.wayne.edu.
Wayne State University · US

Funding

Human Laboratory Model of Cocaine Treatment: Behavioral Economic AnalysisR01DA026861 · NIDA · WAYNE STATE UNIVERSITY · PI GREENWALD, MARK K · 2009 to 2010
$1.4M
NIDA NIH HHS R01 DA026861
6 · The paper itself

Abstract

aimsThe present study examined whether lifetime cocaine use consequences mediate the relationship between trait impulsiveness and current depression symptoms among regular cocaine users.

methodsRegular cocaine users (N=108) were assessed using: Barratt Impulsiveness Scale subscales (non-planning, attentional, motor sub-scales) to measure trait impulsiveness; a standardized Drug History and Use Questionnaire to measure cocaine use and related consequences; and Beck Depression Inventory to measure current depression symptoms.

resultsAll impulsiveness subscales were positively associated with an earlier age of first cocaine use, a higher degree of current depression symptoms and a greater number of lifetime cocaine use consequences. In three separate simple mediation tests, lifetime cocaine use consequences partially mediated the relationship between each of the impulsiveness subscales (non-planning: R(2)=.42; attentional: R(2)=.40; motor: R(2)=.24) and current depression symptoms. Separate moderated mediation analyses failed to demonstrate an interaction between lifetime cocaine use and cocaine-related consequences predicting depression symptoms for the mediation models.

conclusionsCocaine-related consequences function in a more nuanced manner than just an outcome of impulsiveness or cocaine use, but as a pathway between trait impulsiveness and current depression symptoms.

Indexed as

Impulsive BehaviorAdolescentAdultCausalityCocaine-Related DisordersDepressive DisorderFemaleHumansMaleMichiganMiddle AgedPsychiatric Status Rating ScalesSurveys and QuestionnairesYoung AdultCocaineCocaine use consequencesDepressionImpulsivenessPathways

Identifiers

PMID25280245
PMCPMC4252393
OpenAlexW2043925746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.