ArticlePloS one2014
Transcriptional responses of olive flounder (Paralichthys olivaceus) to low temperature.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 92 citations in OpenAlex.
- Integrated Multi-Omics Investigation of Gypenosides' Mechanisms in Lowering Hepatic Cholesterol.Biomolecules · 2025Article
- Temperature-dependent shifts in gut microbiota and metabolome of olive flounder (Paralichthys olivaceus): implications for cold-water aquaculture expansion and probiotic applications.Animal microbiome · 2025Article
- Effects of Environmentally Friendly Aquaculture Chamber Coatings on Enzyme Activities, Histology, and Transcriptome in the Liver of Larimichthys crocea.Marine biotechnology (New York, N.Y.) · 2025Article
- Physiological Traits for Predicting Poleward Extensions in Tropical Fishes: From Lab to Management.Global change biology · 2025Review
- Transcriptomics Reveal the Effects of Breeding Temperature on Growth and Metabolism in the Early Developmental Stage ofBiology · 2023Article
- Transcriptomic Networks Reveal the Tissue-Specific Cold Shock Responses in Japanese Flounder (Biology · 2023Article
- Untargeted LC-MS metabolomics reveals the metabolic responses in olive flounder subjected to hirame rhabdovirus infection.Frontiers in immunology · 2023Article
- Replacement Effect of Fish Meal by Plant Protein Sources in Olive Flounder (Aquaculture nutrition · 2023Article
- Molecular Mechanism Based on Histopathology, Antioxidant System and Transcriptomic Profiles in Heat Stress Response in the Gills of Japanese Flounder.International journal of molecular sciences · 2022Article
- Energy consumption and intestinal microbiome disorders of yellow catfishFrontiers in physiology · 2022Article
- Temperature induces metabolic reprogramming in fish during bacterial infection.Frontiers in immunology · 2022Article
- Identification of Genes Related to Cold Tolerance and Novel Genetic Markers for Molecular Breeding in Taiwan Tilapia (Animals : an open access journal from MDPI · 2021Article
- Transcriptome profiling of olive flounder responses under acute and chronic heat stress.Genes & genomics · 2021Article
- Miocene Diversification and High-Altitude Adaptation ofInsects · 2020Article
- Transcriptomic profiling revealed key signaling pathways for cold tolerance and acclimation of two carp species.BMC genomics · 2020Article
- Transcriptional Programs Underlying Cold Acclimation of Common Carp (Frontiers in genetics · 2020Article
- Transcriptome analyses provide the first insight into the molecular basis of cold tolerance in Larimichthys polyactis.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020Article
- High-throughput sequencing reveals microRNAs in response to heat stress in the head kidney of rainbow trout (Oncorhynchus mykiss).Functional & integrative genomics · 2019Article
- Network of microRNA-transcriptional factor-mRNA in cold response of turbot Scophthalmus maximus.Fish physiology and biochemistry · 2019Article
- Full-length transcriptome of Misgurnus anguillicaudatus provides insights into evolution of genus Misgurnus.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The olive flounder (Paralichthys olivaceus) is an economically important flatfish in marine aquaculture with a broad thermal tolerance ranging from 14 to 23°C. Cold-tolerant flounder that can survive during the winter season at a temperature of less than 14°C might facilitate the understanding of the mechanisms underlying the response to cold stress. In this study, the transcriptional response of flounder to cold stress (0.7±0.05°C) was characterized using RNA sequencing. Transcriptome sequencing was performed using the Illumina MiSeq platform for the cold-tolerant (CT) group, which survived under the cold stress; the cold-sensitive (CS) group, which could barely survive at the low temperature; and control group, which was not subjected to cold treatment. In all, 29,021 unigenes were generated. Compared with the unigene expression profile of the control group, 410 unigenes were up-regulated and 255 unigenes were down-regulated in the CT group, whereas 593 unigenes were up-regulated and 289 unigenes were down-regulated in the CS group. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses revealed that signal transduction, lipid metabolism, digestive system, and signaling molecules and interaction were the most highly enriched pathways for the genes that were differentially expressed under cold stress. All these pathways could be assigned to the following four biological functions for flounder that can survive under cold stress: signal response to cold stress, cell repair/regeneration, energy production, and cell membrane construction and fluidity.
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