ArticleeLife2014
Adaptability of non-genetic diversity in bacterial chemotaxis.
Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 119 citations in OpenAlex.
- Growth-dependent sensory bet-hedging enhances collective navigation.bioRxiv : the preprint server for biology · 2026Article
- The dynamic response of the bacterial flagellar motor to its direct intracellular input signal.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Long-read methylome analysis of Oleidesulfovibrio alaskensis G20 biofilm under copper stress.Scientific reports · 2025Article
- Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy.Nature communications · 2025Article
- Navigated range expansion promotes migratory culling.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Signal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis.Cell systems · 2024Article
- The ability to sense the environment is heterogeneously distributed in cell populations.eLife · 2024Article
- Optimal inference of molecular interaction dynamics in FRET microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Shifts in evolutionary balance of phenotypes under environmental changes.Royal Society open science · 2022Article
- Collective behavior and nongenetic inheritance allow bacterial populations to adapt to changing environments.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Imaging whole-brain activity to understand behavior.Nature reviews. Physics · 2022Article
- Multiple functions of flagellar motility and chemotaxis in bacterial physiology.FEMS microbiology reviews · 2021Review
- Article
- Leave or Stay: Simulating Motility and Fitness of Microorganisms in Dynamic Aquatic Ecosystems.Biology · 2021Article
- Temporal fluctuations in chemotaxis gain implement a simulated-tempering strategy for efficient navigation in complex environments.iScience · 2021Article
- Non-Genetic Diversity in Chemosensing and Chemotactic Behavior.International journal of molecular sciences · 2021Review
- Effect of inoculum size and antibiotics on bacterial traveling bands in a thin microchannel defined by optical adhesive.Microsystems & nanoengineering · 2021Article
- Adaptive tuning of cell sensory diversity without changes in gene expression.Science advances · 2020Article
- Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Maximal information transmission is compatible with ultrasensitive biological pathways.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an alternative, or even evolutionary stepping-stone, to switching between multiple systems. We hypothesized that mutations in gene regulation could lead to heritable control of chemotactic diversity. By simulating foraging and colonization of E. coli using a single-cell chemotaxis model, we found that different environments selected for different behaviors. The resulting trade-offs show that populations facing diverse environments would ideally diversify behaviors when time for navigation is limited. We show that advantageous diversity can arise from changes in the distribution of protein levels among individuals, which could occur through mutations in gene regulation. We propose experiments to test our prediction that chemotactic diversity in a clonal population could be a selectable trait that enables adaptation to environmental variability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.