Evidence map›Paper›PMID 25279561›Full record

ArticlePloS one2014

Experimental comparison of the reproductive outcomes and early development of the offspring of rats given five common types of drinking water.

Hui Zeng, Ji-an Chen, Lin Liu, Da-hua Wang, Wen-juan Fu, Ling-qiao Wang, Jiao-hua Luo, Liang Zhang, Yao Tan, Zhi-qun Qiu and 2 more

Erratum issuedAbstract readComparative Study
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

12 authors.

Hui ZengDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Ji-an ChenDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Lin LiuThe Lundberg-Kienlen Lung Biology and Toxicology Laboratory, Department of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma, United States of America.
Da-hua WangDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Wen-juan FuDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Ling-qiao WangDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Jiao-hua LuoDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Liang ZhangDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Yao TanDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Zhi-qun QiuDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Yu-jing HuangDepartment of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, P. R. China.
Wei-qun Shu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tap water (unfiltered), filtered tap water and processed bottled water (purified water, artificial mineralized water, or natural water) are now the five most widely consumed types of drinking water in China. However, the constituents (organic chemicals and inorganic ingredients) of the five waters differ, which may cause them to have different long-term health effects on those who drink them, especially sensitive children. In order to determine which type of water among the five waters is the most beneficial regarding reproductive outcomes and the developmental behaviors of offspring, two generations of Sprague-Dawley rats were given these five waters separately, and their reproductive outcomes and the developmental behaviors of their offspring were observed and compared. The results showed that the unfiltered tap water group had the lowest values for the maternal gestation index (MGI) and offspring's learning and memory abilities (OLMA); the lowest offspring survival rate was found in the purified water group; and the highest OLMA were found in the filtered tap water group. Thus, the best reproductive and offspring early developmental outcomes were found in the group that drank filtered tap water, which had the lowest levels of pollutants and the richest minerals. Therefore, thoroughly removing toxic contaminants and retaining the beneficial minerals in drinking water may be important for both pregnant women and children, and the best way to treat water may be with granular activated carbon and ion exchange by copper zinc alloy.

Indexed as

Water SupplyAnimalsChinaDrinking WaterEstradiolFemaleFiltrationLearningMaleMemoryPregnancyRatsRats, Sprague-DawleyReproductionTestosteroneWater Pollutants, ChemicalDrinking WaterEstradiolTestosteroneWater Pollutants, Chemical

Identifiers

PMID25279561
PMCPMC4184831

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.