Evidence map›Paper›PMID 25279353›Full record

ReviewFrontiers in cellular and infection microbiology2014

How to find RNA thermometers.

Francesco Righetti, Franz Narberhaus

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Mechanisms of thermoregulation inJournal of bacteriology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Towards the Idea of Molecular Brains.International journal of molecular sciences · 2021
    Review
  7. RNA Secondary Structurome Revealed Distinct Thermoregulation inFrontiers in cell and developmental biology · 2021
    Article
  8. RNA Thermometers in Bacterial Pathogens.Microbiology spectrum · 2018
    Review
  9. Article
  10. Regulation of bacterial heat shock stimulons.Cell stress & chaperones · 2016
    Review
  11. Review
  12. Review
  13. Temperature-responsive in vitro RNA structurome of Yersinia pseudotuberculosis.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  14. Fever as an important resource for infectious diseases research.Intractable & rare diseases research · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francesco RighettiMicrobial Biology, Ruhr University Bochum Bochum, Germany.
Franz NarberhausMicrobial Biology, Ruhr University Bochum Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temperature is one of the decisive signals that a mammalian pathogen has entered its warm-blooded host. Among the many ways to register temperature changes, bacteria often use temperature-modulated structures in the untranslated region of mRNAs. In this article, we describe how such RNA thermometers (RNATs) have been discovered one by one upstream of heat shock and virulence genes in the past, and how next-generation sequencing approaches are able to reveal novel temperature-responsive RNA structures on a global scale.

Indexed as

AnimalsGene Expression Regulation, BacterialHeat-Shock ResponseHost-Pathogen InteractionsHumansNucleic Acid ConformationRNA, BacterialVirulenceRNA, Bacterialheat shocknext-generation sequencingregulatory RNARNA structurevirulence

Identifiers

PMID25279353
PMCPMC4166951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.