ArticleMolecular and clinical oncology2014
Laparoscopic versus open surgery for rectal cancer: Results of a systematic review and meta-analysis on clinical efficacy.
Article in Molecular and clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Mid- and low-rectal cancer: laparoscopic vs open treatment-short- and long-term results. Meta-analysis of randomized controlled trials.International journal of colorectal disease · 2022Pooled it
- Pooled it
- A meta-analysis of short-term outcome of laparoscopic surgery versus conventional open surgery on colorectal carcinoma.Medicine · 2017Pooled it
- Short-term clinical outcomes of laparoscopic vs open rectal excision for rectal cancer: A systematic review and meta-analysis.World journal of gastroenterology · 2017Pooled it
- Pooled it
- Efficacy of transanal tube placement after anterior resection for rectal cancer: a systematic review and meta-analysis.World journal of surgical oncology · 2016Pooled it
- Comparison of multi-modal early oral nutrition for the tolerance of oral nutrition with conventional care after major abdominal surgery: a prospective, randomized, single-blind trial.Nutrition journal · 2017Trial
- Clinical significance of robot-assisted laparoscopic surgery for rectal cancer: a retrospective propensity score matching analysis.Langenbeck's archives of surgery · 2025Article
- Robotic versus open and laparoscopic pelvic exenterations for pelvic cancer: a multicenter propensity-matched analysis in Japan.Surgical endoscopy · 2024Article
- Comparisons of postoperative outcomes of laparoscopic versus open surgery using inverse probability of treatment weighting analysis: an evidence from Iran.BMC surgery · 2024Article
- Real-world impact of laparoscopic surgery for rectal cancer: a population-based analysis.Current oncology (Toronto, Ont.) · 2020Article
- Cost-effectiveness of current approaches in rectal surgery.Annals of medicine and surgery (2012) · 2019Review
- Effects of Permissive Hypercapnia on Laparoscopic Surgery for Rectal Carcinoma.Gastroenterology research and practice · 2019Article
- Isolated rectal cancer surgery: a 2007-2014 population study based on a large administrative database.Updates in surgery · 2017Observational
- Multicentre propensity score-matched analysis of laparoscopic versus open surgery for T4 rectal cancer.Surgical endoscopy · 2017Article
- Robot-assisted intersphincteric resection facilitates an efficient sphincter-saving in patients with low rectal cancer.International journal of colorectal disease · 2017Observational
- Article
- Short-term outcomes after transanal and laparoscopic total mesorectal excision for rectal cancer.Techniques in coloproctology · 2016Article
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer is one of the main malignant tumors threatening human health. Surgery plays a pivotal role in treating colorectal cancer. The present study aimed to compare the clinical effect in patients with rectal cancer undergoing laparoscopic versus open surgery by meta-analysis of the randomized controlled trials (RCTs) published in the past 20 years. The data showed that 14 RCTs comparing laparoscopic surgery with conventional open surgery for rectal cancer matched the selection criteria and reported on 2,114 subjects, of whom 1,111 underwent laparoscopic surgery and 1,003 underwent open surgery for rectal cancer. Blood loss (P<0.00001), days to passage of flatus (P=0.0003), first bowel movement (P=0.0006), fluids intake (P<0.00001), walking independently (P<0.00001), length of hospital duration (P=0.003) and the rate of wound infection (P=0.04) were all significantly reduced following laparoscopic surgery. The incidence of complications, such as ureteric injury (P=0.33), urinary retention (P=0.43), ileus (P=0.05), anastomotic leakage (P=0.09) and incisional hernia (P=0.88), were not significantly different between the two groups. There were no significant differences in lymph nodes harvested (P=0.88), length of specimen (P=0.60), circumferential resection margin (CRM) (P=0.86), regional recurrence ((P=0.08), port site or wound metastasis (P=0.67), distant metastasis (P=0.12), 3-year overall survival (OS) (P=0.42), 3-year disease-free survival (DFS) (P=0.44), 5-year OS (P=0.60) and 5-year DFS (P=0.70). Therefore, laparoscopy for the treatment of patients with rectal cancer has the advantage of recovery and the same complications and prognosis as laparotomy, which indicates that laparoscopy may provide a potential survival benefit for patients with rectal cancer.
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