ArticleMolecular and clinical oncology2014
Double primary hepatic cancer (sarcomatoid carcinoma and hepatocellular carcinoma): A case report.
Article in Molecular and clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Sarcomatoid hepatocellular carcinoma versus conventional hepatocellular carcinoma: a systematic review and meta-analysis.Journal of cancer research and clinical oncology · 2022Pooled it
- Integrated molecular characterization of sarcomatoid hepatocellular carcinoma.Clinical and molecular hepatology · 2025Article
- Preoperative prealbumin-to-fibrinogen ratio to predict survival outcomes in hepatocellular carcinoma patients after hepatic resection.Journal of medical biochemistry · 2022Article
- Clinical and imaging characteristics of primary hepatic sarcomatoid carcinoma and sarcoma: a comparative study.BMC cancer · 2020Article
- A rare case of hepatic sarcomatoid carcinoma: exceeding expectations in a stage IV primary hepatic sarcomatoid carcinoma patient.International journal of clinical and experimental pathology · 2019Article
- Imaging and clinical features of primary hepatic sarcomatous carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2018Article
- Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2018Article
- A Rare Case of Primary Sarcomatous Hepatocellular Carcinoma Without Previous Anticancer Therapy.Journal of clinical and experimental hepatology · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary liver sarcomatoid carcinoma (SC) is a rare and aggressive tumor exhibiting rapid growth and a high recurrence rate following resection. To date, there have been no reports of primary liver SC occurring simultaneously with hepatocellular carcinoma (HCC). This is the case report of a 54-year-old man with liver cirrhosis due to hepatitis B virus (HBV) infection and alcoholic hepatitis. The abdominal computed tomography and magnetic resonance imaging revealed two distinct hepatic masses in a background of hepatic cirrhosis and esophageal varices. Following a clinical diagnosis of two HCCs, a right hepatic lobectomy was performed. Grossly, two distinct lesions were identified: the larger mass was gray to white and well-demarcated, sized 2.5×2.0 cm, located in S5-6, whereas the other was a gray to whitish nodule, sized 1.3×1.0 cm, located in S8. The microscopic analysis revealed that the larger mass was a primary liver SC, which was immunoreactive for cytokeratin (CK) and vimentin (VMT) and negative for hepatocyte-specific antigen (HSA). The other nodule was histologically diagnosed as HCC, which was positive for HSA and CK and negative for HSA, VMT, CK7 and CK19. There was no transition or intermingling lesion between the two tumors. To the best of our knowledge, this is the first case report of double primary liver cancer comprising an SC and a HCC.
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