Evidence map›Paper›PMID 25279175›Full record

ArticleMolecular and clinical oncology2014

Clinical experience with plerixafor as a mobilization regimen for autologous peripheral blood stem cell transplantation in patients with refractory germ cell tumors.

Ignacio García-Escobar, Lucía Parrilla, Laura Montejano Ortega, Daniel Castellanos, María Ángeles Montalbán Pallarés, Hernán Cortés-Funés

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ignacio García-EscobarDepartment of Medical Oncology, University Hospital 12 de Octubre, 28041 Madrid, Spain.
Lucía ParrillaDepartment of Medical Oncology, University Hospital 12 de Octubre, 28041 Madrid, Spain.
Laura Montejano OrtegaDepartment of Hematology and Hemotherapy, University Hospital 12 de Octubre, 28041 Madrid, Spain.
Daniel CastellanosDepartment of Medical Oncology, University Hospital 12 de Octubre, 28041 Madrid, Spain.
María Ángeles Montalbán PallarésDepartment of Medical Oncology, University Hospital 12 de Octubre, 28041 Madrid, Spain.
Hernán Cortés-FunésDepartment of Medical Oncology, University Hospital 12 de Octubre, 28041 Madrid, Spain.
Research Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to report our experience with administration of plerixafor for the mobilization of hematopoietic stem cells (HSCs) in patients with refractory or recurrent germ cell tumors who were candidates for salvage therapy with high-dose chemotherapy and HSC transplantation and for whom mobilization of HSCs had not been achieved by standard therapies. This retrospective and observational study selected patients who were eligible for autologous HSC transplantation (AHSCT) and received plerixafor after failure of HSC mobilization by granulocyte colony-stimulating factor (G-CSF). A total of 5 patients (4 male and 1 female), aged 19-41 years (mean age, 29.6 years) were initially selected. Four patients (80%) achieved an adequate HSC mobilization with plerixafor and subsequently received high-dose chemotherapy followed by HSC transplantation. In these patients, the number of CD34

Indexed as

hematopoietic stem cell transplantationmobilization failuremobilization strategiesplerixafor

Identifiers

PMID25279175
PMCPMC4179799
OpenAlexW2066794103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.