ArticleJournal of geriatric cardiology : JGC2014
Relationship between lipids levels and right ventricular volume overload in congestive heart failure.
Article in Journal of geriatric cardiology : JGC, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Association of the sdLDL-C/lbLDL-C ratio with heart failure beyond conventional LDL-C levels: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Impaired renal blood perfusion is closely related to right heart volume overload in congestive heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Prevalence, Predictors, and Outcomes of Pulmonary Hypertension in Patients with Lupus Nephritis.Medicina (Kaunas, Lithuania) · 2024Article
- A Noninvasive Circulating Signature of Combined Right Ventricular Pressure and Volume Overload in Tetralogy of Fallot/Pulmonary Atresia/Major Aortopulmonary Collateral Arteries.World journal for pediatric & congenital heart surgery · 2024Article
- Blood Cholesterol and Triglycerides Associate with Right Ventricular Function in Pulmonary Hypertension.medRxiv : the preprint server for health sciences · 2024Article
- Therapeutic implications of statins in heart failure with reduced ejection fraction and heart failure with preserved ejection fraction: a review of current literature.F1000Research · 2021Review
- Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease.BMC research notes · 2020Observational
- Statins in the Prevention and Treatment of Heart Failure: a Review of the Evidence.Current atherosclerosis reports · 2019Review
- CHOLESTEROL AND CHLORIDE IN ACUTE HEART FAILURE.Acta clinica Croatica · 2019Observational
- Metabolic Syndrome Modulates Association between Endothelial Lipase and Lipid/Lipoprotein Plasma Levels in Acute Heart Failure Patients.Scientific reports · 2017Observational
- Depression is associated with increased C-reactive protein levels in patients with heart failure and hyperuricemia.Journal of geriatric cardiology : JGC · 2017Article
- Liver abnormalities in pulmonary arterial hypertension.Pulmonary circulationReview
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between lipids and coronary artery disease has been well established. However, this is not the case between lipids and heart failure. Ironically, high lipid levels are associated with better outcomes in heart failure, but the mechanisms underlying the phenomenon are not fully understood. This study was performed to test the hypothesis that reduced intestinal lipid absorption due to venous congestion may lead to low lipid levels.
methodsWe collected data of clinical characteristics, echocardiograph, and lipid profile in 442 unselected patients with congestive heart failure. Correlations between lipid levels [including total cholesterol (TCL), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG)] and right ventricle end diastolic diameter (RVEDD), left ventricle end diastolic diameter (LVEDD), right atrium diameter (RA), left atrium diameter (LA), or left ventricle ejection fraction (LVEF) were analyzed using Pearson correlation and partial correlation. RVEDD, LVEDD, RA, and LA were indexed to the body surface area.
resultsThere was a significantly inverse correlation between TCL levels and RVEDD (r = -0.34, P < 0.001) and RA (r = -0.36, P < 0.001). Other lipids such as LDL-C, HDL-C, and TG had a similar inverse correlation with RVEDD and RA. All these correlations remained unchanged after adjusting for age, gender, smoking status, physical activity levels, comorbidities, and medication use.
conclusionsLipid levels were inversely correlated to RVEDD in patients with congestive heart failure; however, because this was an observational study, further investigation is needed to verify our results as well as identify a causal relationship, if any.
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Registered trials
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