SynthesisWorld journal of gastroenterology2014
Laparoscopic natural orifice specimen extraction-colectomy: a systematic review.
Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 10 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Multi-database bibliometric analysis and cross-database comparison of NOSES research in colorectal cancer: integrated evidence from WoSCC and PubMed.Frontiers in oncology · 2026Pooled it
- Risk of peritoneal metastasis following minimally invasive colectomy for locally advanced colon cancer: a systematic review and meta-analysis.The oncologist · 2025Pooled it
- Laparoscopic natural orifice specimen extraction for diverticular disease: a systematic review.Surgical endoscopy · 2025Pooled it
- Safety and oncological outcomes of natural orifice specimen extraction surgery compared with conventional laparoscopic surgery for right hemicolectomy: a systematic review and meta-analysis.Updates in surgery · 2022Pooled it
- Meta-analysis of natural orifice specimen extraction versus conventional laparoscopy for colorectal cancer.Langenbeck's archives of surgery · 2021Pooled it
- Meta-analysis of laparoscopic anterior resection with natural orifice specimen extraction (NOSE-LAR) versus abdominal incision specimen extraction (AISE-LAR) for sigmoid or rectal tumors.World journal of surgical oncology · 2020Pooled it
- Safety and Oncological Outcomes of Laparoscopic NOSE Surgery Compared With Conventional Laparoscopic Surgery for Colorectal Diseases: A Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Pooled it
- Laparoscopic resection with natural orifice specimen extraction versus conventional laparoscopy for colorectal disease: a meta-analysis.International journal of colorectal disease · 2015Pooled it
- Cosmesis and feasibility of transvaginal natural orifice Specimen extraction (NOSE) for large organ specimen: a prospective pilot study.BMC urology · 2022Trial
- Application of double purse-string anastomosis in optimizing laparoscopic NOSES surgery for rectal cancer under the payment system of DRGs.BMC surgery · 2026Article
- Laparoscopic Resection Rectopexy with Transanal Specimen Extraction for Complete Rectal Prolapse: Retrospective Cohort Study of Functional Outcomes.Journal of clinical medicine · 2026Article
- Clinical progress and technological innovations in sphincter-preserving treatment for ultra-low rectal cancer.Frontiers in oncology · 2026Review
- Laparoscopic-assisted natural orifice specimen extraction subtotal colectomy for redundant colon: a retrospective parallel-cohort comparative study with reduced surgical site infections and accelerated recovery.Frontiers in surgery · 2026Article
- Article
- Natural orifice specimen extraction for diverticular disease: technique, outcomes and role of inflammatory markers.Surgical endoscopy · 2025Article
- The initial experience of natural orifice specimen extraction surgery in laparoscopic colorectal surgery.Turkish journal of surgery · 2025Article
- Transvaginal natural orifice specimen extraction surgery for left-sided colorectal resection: A single-centre cohort study.Journal of minimal access surgery · 2025Article
- Short-term outcomes of Transrectal Natural Orifice Specimen extraction compared with conventional minimally invasive surgery for selected patients with colorectal cancer: a propensity score matching analysis and literature review.World journal of surgical oncology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last 20 years, laparoscopic colorectal surgery has shown equal efficacy for benign and malignant colorectal diseases when compared to open surgery. However, a laparoscopic approach reduces postoperative morbidity and shortens hospital stay. In the quest to optimize outcomes after laparoscopic colorectal surgery, reduction of access trauma could be a way to improve recovery. To date, one method to reduce access trauma is natural orifice specimen extraction (NOSE). NOSE aims to reduce access trauma in laparoscopic colorectal surgery. The specimen is delivered via a natural orifice and the anastomosis is created intracorporeally. Different methods are used to extract the specimen and to create a bowel anastomosis. Currently, specimens are delivered transcolonically, transrectally, transanally, or transvaginally. Each of these NOSE-procedures raises specific issues with regard to operative technique and application. The presumed benefits of NOSE-procedures are less pain, lower analgesia requirements, faster recovery, shorter hospital stay, better cosmetic results, and lower incisional hernia rates. Avoidance of extraction site laparotomy is the most important characteristic of NOSE. Concerns associated with the NOSE-technique include bacterial contamination of the peritoneal cavity, inflammatory response, and postoperative outcomes, including postoperative pain and the functional and oncologic outcomes. These issues need to be studied in prospective randomized controlled trials. The aim of this systematic review is to describe the role of NOSE in minimally invasive colorectal surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.