Evidence map›Paper›PMID 25278577›Full record

ReviewClinical microbiology reviews2014

Coagulase-negative staphylococci.

Karsten Becker, Christine Heilmann, Georg Peters

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 787 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
787citing papers in PubMed, 2 pooled it
35.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

787 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,562 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Emerging microbes & infections · 2026
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  9. Draft genome sequence of a methicillin-resistantMicrobiology resource announcements · 2026
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  16. Clinical implications of a singleJournal of clinical microbiology · 2026
    Article
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727 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karsten BeckerInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany kbecker@uni-muenster.de.
Christine HeilmannInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Georg PetersInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is still based on diagnostic procedures that fulfill the clinical need to differentiate between Staphylococcus aureus and those staphylococci classified historically as being less or nonpathogenic. Due to patient- and procedure-related changes, CoNS now represent one of the major nosocomial pathogens, with S. epidermidis and S. haemolyticus being the most significant species. They account substantially for foreign body-related infections and infections in preterm newborns. While S. saprophyticus has been associated with acute urethritis, S. lugdunensis has a unique status, in some aspects resembling S. aureus in causing infectious endocarditis. In addition to CoNS found as food-associated saprophytes, many other CoNS species colonize the skin and mucous membranes of humans and animals and are less frequently involved in clinically manifested infections. This blurred gradation in terms of pathogenicity is reflected by species- and strain-specific virulence factors and the development of different host-defending strategies. Clearly, CoNS possess fewer virulence properties than S. aureus, with a respectively different disease spectrum. In this regard, host susceptibility is much more important. Therapeutically, CoNS are challenging due to the large proportion of methicillin-resistant strains and increasing numbers of isolates with less susceptibility to glycopeptides.

Indexed as

CoagulaseDisease ManagementDrug Resistance, BacterialHumansMicrobial Sensitivity TestsStaphylococcal InfectionsStaphylococcusCoagulase

Identifiers

PMID25278577
PMCPMC4187637
OpenAlexW2129636343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.