ReviewTrends in cognitive sciences2014
Impaired self-awareness in human addiction: deficient attribution of personal relevance.
Review in Trends in cognitive sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Neuroimaging Impaired Response Inhibition and Salience Attribution in Human Drug Addiction: A Systematic Review.Neuron · 2018Pooled it
- The hyper-sentient addict: an exteroception model of addiction.The American journal of drug and alcohol abuse · 2015Pooled it
- Dissociation of self and mother-related processing in abstinent heroin misusers.Translational psychiatry · 2025Article
- When the Mind Cannot Shift: Cognitive Flexibility Impairments in Methamphetamine-Dependent Individuals.Behavioral sciences (Basel, Switzerland) · 2025Article
- Lifespan investigation of brain volumetric changes associated with substance use disorders.Research square · 2025Article
- Treatment Use Among U.S. Adults with a Substance Use Disorder: Associations with Symptom Severity, Problem Self-Perception, Comorbid Mental Illness, and Mental Health Treatment.International journal of environmental research and public health · 2025Article
- What does a dollar mean to you? utilizing intrinsic rewards within contingency management.Frontiers in psychiatry · 2025Article
- Reward processing deficits: weakened self-reward association in individuals with methamphetamine addiction undergoing abstinence.Frontiers in psychology · 2025Article
- Psychometric Properties of the Turkish Version of the Reflective Functioning Questionnaire in Men on Probation for Substance Use and a Healthy Control Group.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2025Article
- Neuropsychological aspects of self-image in social media use.Frontiers in psychology · 2025Article
- The Limbic System in Co-Occurring Substance Use and Anxiety Disorders: A Narrative Review Using the RDoC Framework.Brain sciences · 2024Review
- Tobacco Images Choice and its Association With Craving and Dependence in People Who Smoke Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Neural Correlates of Metacognition Impairment in Opioid Addiction.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- The distinct functional brain network and its association with psychotic symptom severity in men with methamphetamine-associated psychosis.BMC psychiatry · 2024Article
- Tobacco Images Choice and Its Association with Craving and Dependence in Cigarette Smokers.bioRxiv : the preprint server for biology · 2024Article
- Neurophysiological error processing and addiction self-awareness correlates of reduced insight in cannabis use disorder.Addiction (Abingdon, England) · 2023Article
- A systematic review of sex/gender differences in the multi-dimensional neurobiological mechanisms in addiction and their relevance to impulsivity.Current addiction reports · 2023Article
- Preventing incubation of drug craving to treat drug relapse: from bench to bedside.Molecular psychiatry · 2023Review
- Decoding fMRI alcohol cue reactivity and its association with drinking behaviour.BMJ mental health · 2023Article
- Hungry for compliments? Ghrelin is not associated with neural responses to social rewards or their pleasantness.Frontiers in psychiatry · 2023Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Compromised self-awareness of illness-related deficits and behaviors in psychopathology (e.g., schizophrenia) has been associated with deficient functioning of cortical midline regions including the ventromedial prefrontal cortex (vmPFC), implicated in personal relevance. Here, we review and critically analyze recent evidence to suggest that vmPFC abnormalities could similarly underlie deficient tagging of personal relevance in drug addiction, evidenced by a constellation of behaviors encompassing drug-biased attention, negative outcome insensitivity, self-report/behavior dissociation, and social inappropriateness. This novel framework might clarify, for example, why drug-addicted individuals often ruin long-standing relationships or forego important job opportunities while continuing to engage in uncontrolled drug-taking. Therapeutic interventions targeting personal relevance and associated vmPFC functioning could enhance self-awareness and facilitate more adaptive behavior in this chronically relapsing psychopathology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.