ArticleArchives of women's mental health2015
Psychophysiology and posttraumatic stress disorder symptom profile in pregnant African-American women with trauma exposure.
Article in Archives of women's mental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Efficacy and safety of esketamine for pain control after cesarean delivery: a systematic review and meta-analysis of randomized controlled trials.Frontiers in pharmacology · 2025Pooled it
- Optimizing Outcomes: A Systematic Review of Psychosocial Risk Factors Affecting Perinatal Black/African-American Women with Substance Use Disorder in the United States.Maternal and child health journal · 2022Pooled it
- Longitudinal effects of pregnancy on PTSD symptoms in black female participants: Moderation by sexual trauma and progesterone.Psychoneuroendocrinology · 2025Article
- Windows of change: Revisiting temporal and molecular dynamics of memory reconsolidation and persistence.Neuroscience and biobehavioral reviews · 2025Review
- Conceptualizing disparities and differences in the psychobiology of traumatic stress.Journal of traumatic stress · 2024Review
- From pregnancy to the postpartum: Unraveling the complexities of symptom profiles among trauma-exposed women.Journal of affective disorders · 2024Article
- Hypothalamus and Post-Traumatic Stress Disorder: A Review.Brain sciences · 2023Review
- Linkages Between Childhood Maltreatment, Intimate Partner Violence, and Posttraumatic Stress Disorder Symptoms in Pregnant Hispanic Women: A Network Analysis.Child maltreatment · 2023Article
- Posttraumatic stress disorder, diurnal cortisol, and ambulatory blood pressure in early and late pregnancy.Journal of traumatic stress · 2023Article
- Enduring impact of childhood adversity: Affective modulation of acoustic startle response during pregnancy and postpartum.Physiology & behavior · 2023Article
- Examining the psychometric properties of the PCL-5 in a black community sample using item response theory.Journal of anxiety disorders · 2022Article
- Stress-Related Mental Health Disorders and Inflammation in Pregnancy: The Current Landscape and the Need for Further Investigation.Frontiers in psychiatry · 2022Review
- Using Translational Models of Fear Conditioning to Uncover Sex-Linked Factors Related to PTSD Risk.Journal of psychiatry and brain science · 2022Article
- Using Theories of Posttraumatic Stress to Inform Perinatal Care Clinician Responses to Trauma Reactions.Journal of midwifery & women's health · 2021Review
- Perinatal Insomnia and Mental Health: a Review of Recent Literature.Current psychiatry reports · 2020Review
- The neurobiological basis of sex differences in learned fear and its inhibition.The European journal of neuroscience · 2020Review
- Adverse childhood experiences, posttraumatic stress, and FKBP5 methylation patterns in postpartum women and their newborn infants.Psychoneuroendocrinology · 2020Article
- Trauma, psychiatric disorders, and treatment history among pregnant African American women.Psychological trauma : theory, research, practice and policy · 2020Article
- Neuroendocrine pathways underlying risk and resilience to PTSD in women.Frontiers in neuroendocrinology · 2019Review
- What Does Sex Have to Do with It? The Role of Sex as a Biological Variable in the Development of Posttraumatic Stress Disorder.Current psychiatry reports · 2018Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
While female sex is a robust risk factor for posttraumatic stress disorder (PTSD), pregnant women are an understudied population in regards to PTSD symptom expression profiles. Because circulating hormones during pregnancy affect emotionality, we assessed whether pregnant women would have increased expression of the intermediate phenotypes of hyperarousal and fear-potentiated startle (FPS) compared to non-pregnant women. We examined PTSD symptom profiles in pregnant (n = 207) and non-pregnant women (n = 370). In a second study, FPS responses were assessed in 15 pregnant and 24 non-pregnant women. All participants were recruited from the obstetrics and gynecology clinic at a public hospital serving a primarily African-American, low socioeconomic status, inner-city population. Our results indicate that overall PTSD symptoms were not different between the groups of women. However, pregnant women reported being more hypervigilant (p = 0.036) than non-pregnant women. In addition, pregnant women showed increased FPS to a safety signal compared to non-pregnant women (p = 0.024). FPS to a safety signal in pregnant women was significantly correlated with PTSD hyperarousal symptoms (r = 0.731, p < 0.001). Furthermore, discrimination between danger and safety signals was present in non-pregnant women (p = 0.008), but not in pregnant women (p = 0.895). Together, these data suggest that pregnant women show clinical and psychophysiological hyperarousal compared to non-pregnant women, and support screening for PTSD and assessment of PTSD risk in pregnant women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.