Evidence map›Paper›PMID 25278207›Full record

ArticleInternational urogynecology journal2015

The interaction of stress and urgency urinary incontinence and its effect on quality of life.

Vatché A Minassian, Haiyan Sun, Xiaowei S Yan, Deseraé N Clarke, Walter F Stewart

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Article in International urogynecology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vatché A MinassianBrigham and Women's Hospital, Boston, MA, USA, vminassian@partners.org.
Haiyan Sun
Xiaowei S Yan
Deseraé N Clarke
Walter F Stewart

Funding

Natural History of Stress, Urge and Mixed Urinary Incontinence in WomenR01DK082551 · NIDDK · GEISINGER CLINIC · PI YAN, XIAOWEI SHERRY · 2009 to 2013
$2.6M
NIDDK NIH HHS R01DK082551
6 · The paper itself

Abstract

introduction and hypothesisThe objective was to estimate the impact of stress and urgency urinary incontinence (UI) on the quality of life (QOL), and to determine whether the impact varies according to UI severity.

methodsWe used data from the General Longitudinal Overactive Bladder Evaluation-UI study in women. Stress and urgency UI symptom severity scores ranged from 0 to 8. We used logistic regression to test the relation among different severity levels of stress and urgency UI, and their interaction with the Incontinence Impact Questionnaire (IIQ-7). This was categorized according to percentage ranges as 0-40% (reference), 41-80%, and 81-100%.

resultsBoth stress and urgency UI were significantly associated with IIQ-7. Higher scores had higher odds ratios (ORs). The OR for urgency vs stress UI was greater at the same severity level. For instance, comparing IIQ-7 quintiles (0-40% vs 41-80%), the OR for an association with an urgency UI score of 5-6 was 5.27 (95% CI = 3.78-7.33) vs 2.76 (95% CI = 2.07-3.68) for a stress UI score of 5-6. Both UI subtypes were more strongly related to the upper (81-100%) than the to the lower (41-80%) quintiles. There was a strong positive urgency UI and stress UI interaction with the upper (i.e., 81-100%) but not the two next lower (41-80%) quintiles.

conclusionThe impact of UI subtypes on QOL varies according to the score of IIQ-7, stress and urgency UI, and their interaction. Urgency vs stress UI has a stronger impact. The effect is greatest for high IIQ-7 scores with a significant share mediated by the interaction of the two UI subtypes.

Indexed as

Quality of LifeSeverity of Illness IndexAdultAgedCross-Sectional StudiesFemaleHumansLongitudinal StudiesMiddle AgedOdds RatioRegression AnalysisSurveys and QuestionnairesUrinary Incontinence, StressUrinary Incontinence, Urge

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.