Evidence map›Paper›PMID 25277764›Full record

ArticleInternational journal of hygiene and environmental health2015

Ratio of cord to maternal serum PCB concentrations in relation to their congener-specific physicochemical properties.

Kinga Lancz, Lubica Murínová, Henrieta Patayová, Beata Drobná, Soňa Wimmerová, Eva Sovčíková, Ján Kováč, Dana Farkašová, Irva Hertz-Picciotto, Todd A Jusko and 1 more

Abstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Exposure to Environmental Contaminants and Lung Function in Adolescents-Is There a Link?International journal of environmental research and public health · 2018
    Article
  12. Fetal exposure markers of dioxins and dioxin-like PCBs.Environmental science and pollution research international · 2018
    Article
  13. Article
  14. Partitioning of hexachlorobenzene between human milk and blood lipid.Environmental pollution (Barking, Essex : 1987) · 2017
    Article
  15. Review
  16. Article
  17. Review
  18. The spatial distribution of human exposure to PCBs around a former production site in Slovakia.Environmental science and pollution research international · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kinga LanczSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Lubica MurínováSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Henrieta PatayováSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Beata DrobnáSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Soňa WimmerováSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Eva SovčíkováSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Ján KováčDepartment of Stomatology and Maxillofacial Surgery, Comenius University, Faculty of Medicine in Bratislava, Špitálska 24, 813 72 Bratislava, Slovakia.
Dana FarkašováSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia.
Irva Hertz-PicciottoDivision of Environmental and Occupational Health, Department of Public Health Sciences, School of Medicine, University of California Davis, One Shields Avenue, Med-Sci 1C, Davis, CA, USA.
Todd A JuskoDepartment of Public Health Sciences, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd, CU 420644, Rochester, NY 14642, USA.
Tomáš TrnovecSlovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: tomas.trnovec@szu.sk.

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Early Childhood Development and PCB Exposures in Slovak*R01CA096525 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI HERTZ-PICCIOTTO, IRVA · 2001 to 2005
$2.3M
Women's Health and the Environment over the Entire Lifespan (WHEEL)K12ES019852 · NIEHS · UNIVERSITY OF ROCHESTER · PI CORY-SLECHTA, DEBORAH A · 2010 to 2014
$1.8M
NCI NIH HHS R01 CA096525NCI NIH HHS R01-CA96525NIEHS NIH HHS K12 ES019852NIEHS NIH HHS K12-ES019852NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

The aim was to characterize placental transfer of some congeners of polychlorinated biphenyls (PCBs) and to relate human in utero exposure to these pollutants to their physicochemical properties. We included into the study 1134 births during the period 2002-2003 from two highly PCB contaminated districts in eastern Slovakia. Concentrations of 15 PCB congeners (IUPAC No. 28, 52, 101, 123(+149), 118, 114, 153, 105, 138(+163), 167, 156(+171), 157, 180, 170, and 189) in umbilical cord (C) and maternal serum (M) were determined. The C/M ratios were significantly related, either positively or inversely depending on parameter, to the logarithm of partition coefficient octanol-water (KOW), to fusion enthalpy at the melting point, molecular weight, water solubility, total surface area of the molecule, solvent accessible surface area, melting point, molar volume, and molecular electronegativity distance vector. We found an inverse association between logKOW and lipid adjusted logC/M (const=1.078, b1=-0.179, p<0.001, R(2)=0.039). Parameters evaluated were interrelated except fusion enthalpy at the melting point and electron affinity vs. solubility. We discuss the possible role of cholesterol as a transplacental transporter of PCBs.

Indexed as

Biological TransportFemaleFetal BloodHumansInfant, NewbornLipid MetabolismMaternal-Fetal ExchangePolychlorinated BiphenylsPregnancyRegression AnalysisSlovakiaPolychlorinated BiphenylsPartition coefficient octanol waterPhysicochemical parametersPlacentaPlacental transferPolychlorinated biphenyls

Identifiers

PMID25277764
PMCPMC4256144

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.