ReviewInfectious disease clinics of North America2014
Finding a cure for human immunodeficiency virus-1 infection.
Review in Infectious disease clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Multifarious immunotherapeutic approaches to cure HIV-1 infection.Human vaccines & immunotherapeutics · 2015Trial
- Bryostatin-1 Decreases HIV-1 Infection and Viral Production in Human Primary Macrophages.Journal of virology · 2022Article
- Ethical considerations for HIV remission clinical research involving participants diagnosed during acute HIV infection.BMC medical ethics · 2021Article
- Genome Editing Technologies as Cellular Defense Against Viral Pathogens.Frontiers in cell and developmental biology · 2021Review
- "I would really want to know that they had my back": Transgender women's perceptions of HIV cure-related research in the United States.PloS one · 2020Observational
- RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells.Virology · 2017Article
- Article
- Identification of glycoproteins associated with HIV latently infected cells using quantitative glycoproteomics.Proteomics · 2016Article
- Heat Shock Factor 1 Mediates Latent HIV Reactivation.Scientific reports · 2016Article
- Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA.Journal of clinical microbiology · 2016Article
- Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.Nature biotechnology · 2016Article
- Gp120 binding with DC-SIGN induces reactivation of HIV-1 provirus via the NF-κB signaling pathway.Acta biochimica et biophysica Sinica · 2016Article
- A curative regimen would decrease HIV prevalence but not HIV incidence unless targeted to an ART-naïve population.Scientific reports · 2016Article
- The role of HIV integration in viral persistence: no more whistling past the proviral graveyard.The Journal of clinical investigation · 2016Review
- Restricting retrotransposons: a review.Mobile DNA · 2016Review
- Women in HIV cure research: multilevel interventions to improve sex equity in recruitment.Journal of virus eradicationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Remarkable advances have been made in the treatment of human immunodeficiency virus (HIV)-1 infection, but in the entire history of the epidemic, only 1 patient has been cured. Herein we review the fundamental mechanisms that render HIV-1 infection difficult to cure and then discuss recent clinical and experimental situations in which some form of cure has been achieved. Finally, we consider approaches that are currently being taken to develop a general cure for HIV-1 infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.