Trial reportJournal of clinical laboratory analysis2015
Neutrophil-to-Lymphocyte Ratio Positively Correlates to Age in Healthy Population.
Trial report in Journal of clinical laboratory analysis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic accuracy of routine hematological biomarkers for complications and prognosis in bowel obstruction: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2025Pooled it
- Neutrophil to lymphocyte ratio in Alzheimer's disease: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Pooled it
- Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.Frontiers in immunology · 2025Trial
- Cytotoxic CD4Nature aging · 2026Article
- Leukocyte profiles reveal sex and age differences in immune investment in a polygynous bat.The Journal of animal ecology · 2026Article
- Opposing Association of Lung Neutrophils and PD-L1Aging cell · 2026Article
- Concurrent associations between objective markers and subjective markers of aging with indicators of successful aging: An integrative approach.European journal of ageing · 2026Article
- Elevated neutrophil-to-lymphocyte ratio and the incidence of autoimmune diseases: evidence from a large prospective cohort study.Scientific reports · 2026Article
- Out of the shed and into the field: an immune toolkit for measuring wild ungulate immune phenotypes at multiple scales.Discovery immunology · 2026Article
- Neutrophil-to-lymphocyte ratio in amyotrophic lateral sclerosis: a systematic review and meta-analysis.Brain communications · 2026Review
- Association of neutrophil-lymphocyte ratio with cardiovascular and all-cause mortality in patients receiving chronic hemodialysis: Systematic review and meta-analysis.World journal of methodology · 2025Article
- Age affects the immune system more than a moderate surgical trauma and anesthesia.Scientific reports · 2025Article
- The Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker of Fournier's Gangrene Severity: A Meta-Analysis.Infectious disease reports · 2025Review
- Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker for Long-Term Survival in Older Adults at a Mental Health Care Center: A Historical Cohort Analysis.Journal of clinical medicine · 2025Article
- Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study.Frontiers in medicine · 2025Article
- Association of Naples Prognostic Score with anemia in cancer survivors: a study based on NHANES database.Frontiers in oncology · 2025Article
- Radiotherapy and inflammaging: the influence of prostate cancer radiotherapy on systemic inflammation.World journal of urology · 2024Article
- Evaluating the Role of CBC-Derived Indices in Children with Hashimoto's Thyroiditis.Diagnostics (Basel, Switzerland) · 2024Article
- Time is encoded by methylation changes at clustered CpG sites.bioRxiv : the preprint server for biology · 2024Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeutrophil to lymphocyte ratio (NLR) was reported to be an independent easy-to-measure marker for many diseases, while the distribution of NLR in healthy population was not formally studied. So we investigated NLR in healthy people in this study.
methodsData include NLR, systolic pressure, diastolic pressure, and body mass index (BMI), which were collected from 3,262 healthy population. Correlations of NLR with variables were analyzed with SPSS16.0.
resultsResults demonstrated that NLR was positively associated with age (P < 0.001). The eldest age group possessed the highest NLR and the youngest age group had the lowest NLR. NLR was also slightly positively associated with systolic pressure, diastolic pressure, and BMI (P < 0.001).
conclusionOlder people possessed relatively high NLR in healthy population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.