ArticleJournal of caring sciences2013
The Impact of Aloe vera and Calendula on Perineal Healing after Episiotomy in Primiparous Women: A Randomized Clinical Trial.
Article in Journal of caring sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review.BMC veterinary research · 2019Pooled it
- The effect of the Verbascum Thapsus on episiotomy wound healing in nulliparous women: a randomized controlled trial.BMC complementary medicine and therapies · 2021Trial
- A Step-by-Step Protocol for the Isolation ofBio-protocol · 2026Article
- Healing-assessment tools for perineal and cesarean section wounds in postpartum women: A scoping review.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Effect of oral sesame oil gelatin capsules on episiotomy pain in primiparous women: a triple-blind randomized controlled trial.Maternal health, neonatology and perinatology · 2025Article
- Revolutionizing Wound Healing: Unleashing Nanostructured Lipid Carriers Embodied with Herbal Medicinal Plant.Current pharmaceutical biotechnology · 2025Review
- Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences.Heliyon · 2024Review
- Phytochemistry and Biological Activity of Medicinal Plants in Wound Healing: An Overview of Current Research.Molecules (Basel, Switzerland) · 2022Review
- Effect of Complementary Medicine on Pain Relief and Wound Healing after Cesarean Section: A Systematic Review.Journal of pharmacopuncture · 2021Review
- Public Knowledge, Attitude, and Practice on Herbal Remedies Used During Pregnancy and Lactation in West Bank Palestine.Frontiers in pharmacology · 2020Article
- [Evidence-Based Practices in Episiotomy Care].Florence Nightingale hemsirelik dergisi · 2019Article
- Impact of Hypericum Perforatum Ointment on Perineal Pain Intensity Following Episiotomy: a Randomized Placebo-Controlled Trial.Journal of caring sciences · 2018Article
- Preclinical evaluation of collagen type I scaffolds, including gelatin-collagen microparticles and loaded with a hydroglycolic Calendula officinalis extract in a lagomorph model of full-thickness skin wound.Drug delivery and translational research · 2016Article
- Smart Dressings Based on Nanostructured Fibers Containing Natural Origin Antimicrobial, Anti-Inflammatory, and Regenerative Compounds.Materials (Basel, Switzerland) · 2015Review
- The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds.BioMed research international · 2015Review
- Some questions about herbal and traditional medicine.Nursing and midwifery studies · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEpisiotomy is used for enlarging the perineum. Aloe vera and Calendula have been used for treating different diseases from ancient times, limited researches have been done regarding the healing of these plants. Since the effect of their ointment on episiotomy healing has not been studied, this study is being done for determining the impact of Aloe vera and Calendula on episiotomy healing in primiparous women.
methodsThis clinical trial involves 111 qualified primiparous women admitted in Lolagar hospital. They were randomly categorized into three groups of control (n=1) and experimental (n=2) groups. The women in experimental group used Aloe vera and Calendula Ointment every 8 hours and the control group used hospital routine on episiotomy for 5 days. The data were collected by demographic questionnaire and redness, edema, ecchymosis, discharge and approximation scale (REEDA) which investigated the episiotomy healing before and five days after intervention in two groups. ANOVA, Tukey test, Kruskal-wallis, Chi-square were used for data analysis.
resultsThe three groups do not have statistically significant different regarding demographic and other intervening variables. Comparing the mean of REEDA in five days after delivery showed statistically significant difference between control and experimental groups.
conclusionAccording to the results, using Aloe vera and Calendula ointment considerably increases the speed of episiotomy wound healing so it can be used for quickening the episiotomy healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.