ArticleRehabilitation research and practice2014
Clinical understanding of spasticity: implications for practice.
Article in Rehabilitation research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07303582 (Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities), which is not on this map. Cited by 52 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities (ICE): a Pilot Randomised Controlled Trial
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Comparative pharmacotherapeutic efficacy and dose-related safety profiles of intrathecal baclofen: a systematic review and meta-analysis in neurological spasticity.Frontiers in pharmacology · 2026Pooled it
- Evaluation of stem/stromal cell transplantation safety and efficacy in children diagnosed with cerebral palsy: A systematic review and meta-analysis of randomized controlled trials.Stem cell research & therapy · 2025Pooled it
- The effects of serial casting on lower limb function for children with Cerebral Palsy: a systematic review with meta-analysis.BMC pediatrics · 2020Pooled it
- Effects of the Structured Water Dance Intervention (SWAN) on muscular hypertonia in adults with profound intellectual and multiple disabilities.Scientific reports · 2022Trial
- Mindfulness Meditation Effects on Poststroke Spasticity: A Feasibility Study.Journal of evidence-based integrative medicineTrial
- The Role of Radial Shockwave Therapy in Reducing Spasticity and Improving Upper-Limb Function Following Stroke.Journal of clinical medicine · 2026Article
- The Benefits of Advanced Botulinum Neurotoxin Injection Training from a Spasticity Management Fellowship.Toxins · 2026Article
- Powered Exoskeleton Gait Training and Hip Rate of Force Development in Chronic Hypoxic-Ischemic Encephalopathy: A Case Study.Brain sciences · 2026Article
- Enhancing Cardiopulmonary Function Through Spasticity Reduction-Effects of Botulinum Toxin A After Stroke: A Prospective Before-After Study.Medicina (Kaunas, Lithuania) · 2026Article
- Review
- Patient-Centred and Daily Life-Oriented Botulinum Toxin Treatment for Stroke Survivors with Upper Extremity Spasticity-Effects and Practical Aspects.Journal of clinical medicine · 2025Article
- Predicting inpatient rehabilitation length of stay for adults with traumatic spinal cord injury.The journal of spinal cord medicine · 2025Article
- Psychometric validation of comprehensive coordination scale to assess the advanced coordination ability in people with stroke.European journal of physical and rehabilitation medicine · 2025Article
- Clinical utility of a patient-reported outcome for assessing spasticity in a pediatric population.Journal of pediatric rehabilitation medicine · 2025Article
- Percutaneous Spinal Cord Stimulator Enables Novel Clonus Biomarker and Management in Persons With Spinal Cord Injury and Multiple Sclerosis: An Exploratory Study.Topics in spinal cord injury rehabilitation · 2025Article
- Impacts of hippotherapy simulation on balance, postural control, and spasticity of thigh adductor muscles in children with spastic bilateral Cerebral Palsy: A single-blind clinical trial study.Iranian journal of child neurology · 2025Article
- Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study.Frontiers in physiology · 2025Article
- Article
- Excitation-inhibition imbalance in the motor control network: a key factor in post-stroke spasticity.Frontiers in human neuroscience · 2025Review
- Localizing motor entry points of adductor muscles of thigh for motor point procedures in the treatment of adductor spasticity.Anatomy & cell biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spasticity is a poorly understood phenomenon. The aim of this paper is to understand the effect of spasticity on daily life and identify bedside strategies that enhance patient's function and improve comfort. Spasticity and clonus result from an upper motor neuron lesion that disinhibits the tendon stretch reflex; however, they are differentiated in the fact that spasticity results in a velocity dependent tightness of muscle whereas clonus results in uncontrollable jerks of the muscle. Clinical strategies that address function and comfort are paramount. This is a secondary content analysis using a qualitative research design. Adults experiencing spasticity associated with neuromuscular disorder were asked to participate during inpatient acute rehabilitation. They were asked to complete a semistructured interview to explain and describe the nature of their experienced spasticity on daily basis. Spasticity affects activities of daily living, function, and mobility. Undertreated spasticity can lead to pain, immobility, and risk of falls. There were missed opportunities to adequately care for patients with spasticity. Bedside care strategies identified by patients with spasticity are outlined. Uses of alternative therapies in conjunction with medications are needed to better manage spasticity. Patient reports on spasticity are important and should be part of clinical evaluation and practice.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.