Evidence map›Paper›PMID 25276371›Full record

ArticleJournal of thoracic disease2014

FDG PET-CT combined with TBNA for the diagnosis of atypical relapsing polychondritis: report of 2 cases and a literature review.

Wei Lei, Da-Xiong Zeng, Tao Chen, Jun-Hong Jiang, Chang-Guo Wang, Ye-Han Zhu, Jian-An Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of thoracic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Diagnosis value ofBMC medical imaging · 2023
    Pooled it
  2. Review
  3. Imaging features and clinical value ofArthritis research & therapy · 2023
    Article
  4. Article
  5. [Diagnosis and treatment of laryngotracheal stenosis induced by relapsing polychondritis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  6. IsArthritis research & therapy · 2019
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei LeiDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Da-Xiong ZengDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Tao ChenDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Jun-Hong JiangDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Chang-Guo WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Ye-Han ZhuDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Jian-An HuangDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
First Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the value of (18)F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) combined with transbronchial needle aspiration (TBNA) in diagnosing atypical relapsing polychondritis (RP).

methodsData from two patients with atypical RP, which had been diagnosed in our hospital using FDG PET-CT combined with TBNA, were retrospectively analyzed. A review of the relevant literature was also performed.

resultsConsistent with the previously reported 20 cases of RP that had been diagnosed using FDG PET-CT, the two patients in the present study showed the involvement of multiple organs, including the nose, throat, trachea, bronchi, costicartilage and joint cartilages, and increased FDG uptake was found in these areas. The mean value of SUVmax was 5.14. PET-CT revealed that 86.4% of the patients with RP had airway involvement. TBNA technique was used for biopsy of the hypermetabolic lesions, and pathologic examinations confirmed the diagnosis of RP. The time to diagnosis in these two patients and the 20 cases reported previously was about 6.9 months, significantly shorter than the average diagnosis time (20 months).

conclusionsFDG PET-CT has several advantages for diagnosing RP, especially atypical RP. TBNA is a minimally invasive and safe technique for obtaining airway cartilage. Combining PET-CT with TBNA may play an important role in shortening the time to diagnosis in patients with RP involvement of airway.

Indexed as

cartilagefluorodeoxyglucose (FDG)positron emission tomography-computed tomography (PET-CT)Relapsing polychondritis (RP)standard uptake value (SUV)transbronchial needle aspiration (TBNA)

Identifiers

PMID25276371
PMCPMC4178094
OpenAlexW2178171184

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.