ArticleWorld journal of gastrointestinal surgery2014
Increased postoperative complications after protective ileostomy closure delay: An institutional study.
Article in World journal of gastrointestinal surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02669992 (Loop Ileostomy Closure.Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site in the Abdominal Wall. A Prospective Randomised Multicenter Trial.), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Loop Ileostomy Closure.Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site in the Abdominal Wall. A Prospective Randomised Multicenter Trial.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Enhanced recovery after surgery (ERAS) in stoma reversal surgery: a systematic review and meta-analysis.Updates in surgery · 2025Pooled it
- Risk factors and incidence of surgical wound infection after stoma reversal: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis.Surgical endoscopy · 2019Pooled it
- Negative-pressure wound therapy after stoma reversal in colorectal surgery: a randomized controlled trial.BJS open · 2021Trial
- Early versus conventional stoma closure following bowel surgery: A randomized controlled trial.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationTrial
- Predictors of clinically significant complications after stoma reversal: A prospective analytical study.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Risk factors for infectious enteritis after temporary stoma closure following colorectal cancer surgery: a retrospective cohort study.Annals of medicine and surgery (2012) · 2026Article
- Risk factors for non-reversal of diverting ileostomies: a retrospective analysis of 456 patients.International journal of colorectal disease · 2026Article
- A predictive tool for postoperative ileus after ileostomy closure: Model development and validation.Turkish journal of surgery · 2025Article
- Increased risk of postoperative complications after delayed stoma reversal: a multicenter retrospective cohort study on patients undergoing anterior resection for rectal cancer.International journal of colorectal disease · 2025Article
- Early vs. Late Stoma Reversal After Open Low Anterior Resection Post-Neoadjuvant Chemoradiotherapy.Indian journal of surgical oncology · 2025Article
- The impact of anastomotic leakage characteristics on the occurrence of anastomotic stenosis after colorectal resection, a retrospective cohort study.International journal of colorectal disease · 2024Article
- Does one-stitch method of temporary ileostomy affect the stoma-related complications after laparoscopic low anterior resection in rectal cancer patients?European journal of medical research · 2024Article
- The impact of delayed closure of ileostomy on postoperative complications in patients with Crohn's disease: a case-matched study.Updates in surgery · 2024Article
- Early diverting stoma closure is feasible and safe: results from a before-and-after study on the implementation of an early closure protocol at a tertiary referral center.Techniques in coloproctology · 2024Article
- Application and evaluation of transitory protective stoma in ovarian cancer surgery.Frontiers in oncology · 2023Review
- The impact of prolonged delay to loop ileostomy closure on postoperative morbidity and hospital stay: A retrospective cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Review
- Effect of closed incision negative pressure wound therapy on incidence rate of surgical site infection after stoma reversal: a pilot study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2021Article
- Impact of timing of reversal of loop ileostomy on patient outcomes: a retrospective cohort study.Techniques in coloproctology · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the morbidity and complications associated to ileostomy reversal in colorectal surgery patients, and if these are related to the time of closure.
methodsA retrospective analysis of 93 patients, who had undergone elective ileostomy closure between 2009 and 2013 was performed. Demographic, clinical and surgical variables were reviewed for analysis. All complications were recorded, and classified according to the Clavien-Dindo Classification. Statistical univariate and multivariate analysis was performed, setting a P value of 0.05 for significance.
resultsThe patients had a mean age of 60.3 years, 58% male. The main procedure for ileostomy creation was rectal cancer (56%), and 37% had received preoperative chemo-radiotherapy. The average delay from creation to closure of the ileostomy was 10.3 mo. Postoperative complications occurred in 40% of the patients, with 1% mortality. The most frequent were ileus (13%) and wound infection (13%). Pseudomembranous colitis appeared in 4%. Increased postoperative complications were associated with delay in ileostomy closure (P = 0.041). Male patients had more complications (P = 0.042), mainly wound infections (P = 0.007). Pseudomembranous colitis was also associated with the delay in ileostomy closure (P = 0.003). End-to-end intestinal anastomosis without resection was significantly associated with postoperative ileus (P = 0.037).
conclusionAlthough closure of a protective ileostomy is a fairly common surgical procedure, it has a high rate of complications, and this must be taken into account when the indication is made. The delay in stoma closure can increase the rate of complications in general, and specifically wound infections and colitis.
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