ArticleIranian journal of pharmaceutical research : IJPR2014
Microencapsulation of Probiotics by Calcium Alginate-gelatinized Starch with Chitosan Coating and Evaluation of Survival in Simulated Human Gastro-intestinal Condition.
Article in Iranian journal of pharmaceutical research : IJPR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 130 citations in OpenAlex.
- Safety and Effectiveness of Probiotic Preparations: A Contemporary Review.Diseases (Basel, Switzerland) · 2026Review
- Enhanced Storage Stability and Gastrointestinal Survival of Lactiplantibacillus plantarum by Sodium Alginate-Resistant Starch-EGCG Composite Encapsulation.Journal of food science · 2026Article
- Application of Natural Polymers to Enhance Probiotic Stability Following the Spray Freeze Drying Method.Probiotics and antimicrobial proteins · 2026Article
- Preparation, Characterization, and In Vitro Digestion Behavior of Alginate-Chitosan Microspheres Loaded withFoods (Basel, Switzerland) · 2026Article
- Encapsulated probiotics and nanoprobiotics - Biocompatible materials, processing technologies, and applications: A review.Biomolecules & biomedicine · 2025Review
- Vegan Sesame Milk Ice Cream With Probiotic Bacteria (Food science & nutrition · 2025Article
- Encapsulation of Acid Whey in Alginate Microspheres for Application in Skin Microbiome-Friendly Topical Formulations: Optimization Through a Design of Experiments Approach.Molecules (Basel, Switzerland) · 2025Article
- Encapsulation of L. fermentum with chitosan-alginate enhances its bioactivity against acrylamide toxicity in D.mel.Scientific reports · 2025Article
- Inducing Drought Resilience in Maize Through Encapsulated Bacteria: Physiological and Biochemical Adaptations.Plants (Basel, Switzerland) · 2025Article
- Development of Chitosan-Polyacrylic Acid Complex Systems for Enhanced Oral Delivery ofDrug design, development and therapy · 2025Article
- Exploring Calcium Alginate-Based Gels for Encapsulation ofGels (Basel, Switzerland) · 2024Article
- Effect of Encapsulation ofACS applied materials & interfaces · 2024Article
- A Functional Bread Fermented withCurrent developments in nutrition · 2024Article
- Encapsulation of Bifidobacterium animalis subsp. lactis Through Emulsification Coupled with External Gelation for the Development of Synbiotic Systems.Probiotics and antimicrobial proteins · 2023Article
- Review
- Rice bran as an encapsulating material to produce a healthy synbiotic product with improved gastrointestinal tolerance.Archives of microbiology · 2023Article
- Delivery ofGels (Basel, Switzerland) · 2023Article
- Journey of the Probiotic Bacteria: Survival of the Fittest.Microorganisms · 2022Review
- Preparation and Characteristics of Alginate Microparticles for Food, Pharmaceutical and Cosmetic Applications.Polymers · 2022Review
- Materials Used for the Microencapsulation of Probiotic Bacteria in the Food Industry.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microencapsulation as one of the most modern methods has considerable effects on probiotic survival. In this study Lactobacillus casei (ATCC 39392) and Bifidobacterium bifidum (ATCC 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and were incubated in simulated gastric juice (along with pepsin, pH=1.5) and simulated intestinal juice (along with pancreatin and bile salts, pH = 8) for 2 hours at 37 (o)C. The morphology and size of microcapsules were measured by scanning electron and optical microscopy. The results indicated that the survival of microencapsulated probiotic increased significantly in simulated gastro-intestinal condition (P < 0.05). Chitosan coating played a significant role in the protection of probiotic bacteria in simulated gastro-intestinal condition and the diameter of the microcapsules increased with the addition of chitosan coating. In general, this study indicated that microencapsulation with alginate-gelatinized starch coated with chitosan could successfully and significantly protect probiotic bacteria against adverse condition of simulated human gastro-intestinal condition.
Indexed as
Identifiers
25276184PMC4177644W2170396274What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.