Evidence map›Paper›PMID 25275695›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2015

Race differences in the association between multivitamin exposure and wheezing in preterm infants.

A M Hibbs, D C Babineau, X Wang, S Redline

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
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  6. Article
  7. The problems of moderate preterm infants.Seminars in perinatology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

A M Hibbs1] Department of Pediatrics, Case Western Reserve School of Medicine, Cleveland, OH, USA [2] Division of Neonatology, Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
D C Babineau1] Center for Clinical Investigation, Case Western Reserve School of Medicine, Cleveland, OH, USA [2] Rho Federal Systems Division, Chapel Hill, NC, USA.
X WangCenter for Clinical Investigation, Case Western Reserve School of Medicine, Cleveland, OH, USA.
S Redline1] Center for Clinical Investigation, Case Western Reserve School of Medicine, Cleveland, OH, USA [2] Department of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital · USCase Western Reserve University · USRainbow Babies & Children's Hospital · USRho (United States) · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Gastrointestinal Risk Factors for Wheezing in Premature InfantsK23HD056299 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI HIBBS, ANNA MARIA · 2007 to 2011
$651k
NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1TR000439NICHD NIH HHS K23 HD056299NICHD NIH HHS K23HD056299
6 · The paper itself

Abstract

objectiveWe aimed to determine whether vitamin D exposure, as estimated by use of multivitamins, is positively or negatively associated with recurrent wheezing in infants born preterm. STUDY

designThis prospective cohort study enrolled 300 infants, born at 28(0/7) to 34(6/7) weeks gestational age, and conducted follow-up at 3-, 6-, 9- and 12-month adjusted age.

resultBlack (55.9%) and non-black (36.6%) infants experienced recurrent wheezing. Adjusted odds ratios (ORs) for the association between multivitamin exposure at 3 months and recurrent wheezing were 2.15 (95% confidence interval (CI): 0.97, 4.75) for black and 0.43 (95% CI: 0.19, 0.96) for non-black infants with an interaction by race (P=0.003). In lag-effect models, ORs were 2.69 (95% CI: 1.41, 5.14) for black and 0.50 (95% CI: 0.27, 0.92) for non-black infants.

conclusionDifferences by race were seen in association between multivitamins and wheezing; population heterogeneity should be considered when evaluating vitamin supplementation.

Indexed as

AsianBlack or African AmericanDietary SupplementsFemaleFollow-Up StudiesGestational AgeHumansInfant, NewbornInfant, PrematureMaleOdds RatioProspective StudiesRespiratory SoundsVitamin DWhite PeopleVitamin D

Identifiers

PMID25275695
PMCPMC4342282
OpenAlexW2049819877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.