Evidence map›Paper›PMID 25275169›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2014

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.

Manolis Kellis, Barbara Wold, Michael P Snyder, Bradley E Bernstein, Anshul Kundaje, Georgi K Marinov, Lucas D Ward, Ewan Birney, Gregory E Crawford, Job Dekker and 20 more

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors.

Manolis Kellis
Barbara Wold
Michael P Snyder
Bradley E Bernstein
Anshul Kundaje
Georgi K Marinov
Lucas D Ward
Ewan Birney
Gregory E Crawford
Job Dekker
Ian Dunham
Laura L Elnitski
Peggy J Farnham
Elise A Feingold
Mark Gerstein
Morgan C Giddings
David M Gilbert
Thomas R Gingeras
Eric D Green
Roderic Guigo
Tim Hubbard
Jim Kent
Jason D Lieb
Richard M Myers
Michael J Pazin
Bing Ren
John Stamatoyannopoulos
Zhiping Weng
Kevin P White
Ross C Hardison

Funding

Regulatory and epigenetic landscapes reveal biological processes, disease mechanisms and diagnostic markersZIAHG200323 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI ELNITSKI, LAURA L · 2009 to 2025
$27.6M
GENCODE Resource ProjectU41HG007234 · NHGRI · SANGER INSTITUTE · PI FLICEK, PAUL · 2013 to 2020
$20.3M
UNDERSTANDING MECHANISMS OF hESC SELF-RENEWAL AND CELL FATE COMMITMENTP01GM085354 · NIGMS · UNIVERSITY OF GEORGIA · PI DALTON, STEPHEN · 2008 to 2018
$18.3M
Structural Annotation of the Human GenomeR01HG003143 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Job Dekker · 2003 to 2026
$15.4M
Landscape of transcription in human and mouseU54HG007004 · NHGRI · COLD SPRING HARBOR LABORATORY · PI GINGERAS, THOMAS RAYMOND · 2012 to 2017
$10.6M
Genome Plasticity during ES Cell Differentiation to Neural LineagesR01GM083337 · NIGMS · SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE · PI David M Gilbert · 2007 to 2026
$6.1M
NHGRI NIH HHS U41 HG007234NHGRI NIH HHS U54 HG007004NIGMS NIH HHS R01 GM083337
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNAGenome, HumanHumansDNA

Identifiers

PMID25275169
PMCPMC4143047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.