ArticlePediatric radiology2015
Estimated risk of radiation-induced cancer from paediatric chest CT: two-year cohort study.
Article in Pediatric radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis.BMC pulmonary medicine · 2018Review
- Projected cancer risks potentially related to past, current, and future practices in paediatric CT in the United Kingdom, 1990-2020.British journal of cancer · 2017Article
- Evaluation of Image Quality of Overweight and Obese Patients in CT Using High Data Rate Detectors.In vivo (Athens, Greece)Article
- Factors Associated With CT Scan Repetition in Pediatrics and Its Relationship With Cancer Risk: A Systematic Review and Meta-Analysis.Dose-response : a publication of International Hormesis SocietyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe increasing absolute number of paediatric CT scans raises concern about the safety and efficacy and the effects of consecutive diagnostic ionising radiation.
objectiveTo demonstrate a method to evaluate the lifetime attributable risk of cancer incidence/mortality due to a single low-dose helical chest CT in a two-year patient cohort. MATERIALS AND
methodsA two-year cohort of 522 paediatric helical chest CT scans acquired using a dedicated low-dose protocol were analysed retrospectively. Patient-specific estimations of radiation doses were modelled using three different mathematical phantoms. Per-organ attributable cancer risk was then estimated using epidemiological models. Additional comparison was provided for naturally occurring risks.
resultsTotal lifetime attributable risk of cancer incidence remains low for all age and sex categories, being highest in female neonates (0.34%). Summation of all cancer sites analysed raised the relative lifetime attributable risk of organ cancer incidence up to 3.6% in female neonates and 2.1% in male neonates.
conclusionUsing dedicated scan protocols, total lifetime attributable risk of cancer incidence and mortality for chest CT is estimated low for paediatric chest CT, being highest for female neonates.
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Registered trials
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