ReviewClinical reviews in allergy & immunology2015
The Clinical Features of Sarcoidosis: A Comprehensive Review.
Review in Clinical reviews in allergy & immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
90 citing papers in PubMed, 1 synthesis or guideline pooled it, 264 citations in OpenAlex.
- Granulomatous Sarcoidosis Mimics.Frontiers in medicine · 2021Pooled it
- Acceptability of a Dyadic Tai Chi Intervention for Older People Living With Dementia and Their Informal Carers.Journal of aging and physical activity · 2019Trial
- Derivation of a peripheral blood-based transcriptomic risk score for extrapulmonary sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- A Rare Presentation of Sarcoidosis: A Case of Acute Onset Bilateral Pulmonary Infiltrates and Skin Lesions.Annals of African medicine · 2026Article
- Miliary lungs in a septuagenarian: Thinking beyond tuberculosis.Lung India : official organ of Indian Chest Society · 2026Article
- The coincidental association between isotretinoin therapy and onset of pachydermodactyly: A case report.JAAD case reports · 2026Article
- Associations of Systemic Immune-Inflammation Index and Hematological Markers with Symptom Burden and Radiological Stage in Sarcoidosis.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Advances in management of sarcoidosis-associated fatigue: A narrative review.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- Case report on investigational modular cardiac rhythm management system: wireless communication between leadless pacemaker and subcutaneous defibrillator in cardiac sarcoidosis with limited vascular access.European heart journal. Case reports · 2026Article
- Assessment of sarcopenia in female patients with sarcoidosis upon initial diagnosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- Lofgren's syndrome: A clinical puzzle in a case of monoarthritis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- Cardiac sarcoidosis: from clinical manifestations to heart transplantation.Frontiers in medicine · 2026Review
- A Rare Case of Sarcoidosis presenting as a Lung Mass with Treatment AssociatedRadiology case reports · 2025Article
- Salivary Gland Sarcoidosis: Systematic Review of Case Reports and Case Series.Journal of clinical medicine · 2025Review
- Article
- Assessment of Disease Burden Among Japanese Patients With Pulmonary Sarcoidosis: A Questionnaire-Based Study.Cureus · 2025Article
- Lofgren Syndrome in a 35-Year-Old Female: A Case Report.Clinical case reports · 2025Article
- Age, comorbidity, race and gender differences in referral to a pulmonologist among patients with sarcoidosis at a large academic medical center.BMC pulmonary medicine · 2025Article
- An Unusual Case of Renal-Limited Sarcoidosis Presenting With Hypercalcemia of Unknown Origin: A Case Report.Cureus · 2025Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcoidosis has innumerable clinical manifestations, as the disease may affect every body organ. Furthermore, the severity of sarcoidosis involvement may range from an asymptomatic state to a life-threatening condition. This manuscript reviews a wide variety of common and less common clinical characteristics of sarcoidosis. These manifestations are presented organ by organ, although additional sections describe systemic and multiorgan presentations of sarcoidosis. The lung is the organ most commonly involved with sarcoidosis with at least 90 % of sarcoidosis patients demonstrating lung involvement in most series. The skin, eye, liver, and peripheral lymph node are the next most commonly clinically involved organs in most series, with the frequency of involvement ranging from 10 to 30 %. The actual frequency of sarcoidosis organ involvement is probably much higher as it is frequently asymptomatic and may avoid detection. This is particularly common with lung, liver, cardiac, and bone involvement. Cardiac sarcoidosis is present in 25 % of all sarcoidosis but only causes clinical problems in 5 % of them. Nevertheless, unlike sarcoidosis involvement of most other organs, it may be suddenly fatal. Therefore, it is important to screen for cardiac sarcoidosis in all sarcoidosis patients. All sarcoidosis patients should also be screened for eye involvement as asymptomatic patients may have eye involvement that may cause permanent vision impairment. Pulmonary fibrosis from sarcoidosis is usually slowly progressive but may be life-threatening because of the development of respiratory failure, pulmonary hypertension, or hemoptysis related to a mycetoma or bronchiectasis. Some manifestations of sarcoidosis are not organ-specific and probably are the result of a release of mediators from the sarcoid granuloma. Two such manifestations include small fiber neuropathy and fatigue syndromes, and they are observed in a large percentage of patients.
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