ArticleJournal of veterinary internal medicine
A retrospective study of 1,098 blood samples with anemia from adult cats: frequency, classification, and association with serum creatinine concentration.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Clinical insights into Candidatus Mycoplasma haemominutum-associated anaemia in naturally infected cats: flea-associated risk and paradoxical clinicopathological findings.Irish veterinary journal · 2026Article
- Plasma Multi-Metal Exposure, Renal Function, and Anemia Risk in Rural China: The Mediating Role of Serum Creatinine.Biological trace element research · 2026Article
- Long-term efficacy of cyclosporine and interferon-ω in feline chronic gingivostomatitis: insights from SDAI scores.BMC veterinary research · 2025Article
- Prevalence of ocular lesions in cats with anaemia and thrombocytopenia.Journal of feline medicine and surgery · 2025Article
- Regenerative anemia identification in cats: Red blood cell indices or morphology, what to use?Veterinary world · 2024Article
- Mesenchymal stromal cell therapy for feline chronic gingivostomatitis: Long term experience.Frontiers in veterinary science · 2023Article
- Effects of the solid lipid nanoparticle of carvacrol on rodents with lung injury from smoke inhalation.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
- Feline non-regenerative anemia: Diagnostic and treatment recommendations.Journal of feline medicine and surgery · 2019Article
- Diagnostic performances of manual and automated reticulocyte parameters in anaemic cats.Journal of feline medicine and surgery · 2018Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFrequency and classification of anemia in terms of regeneration status and erythrocyte indices are not well described in cats.
objectiveTo determine frequency and regenerative status of anemia in samples from adult cats, to assess the sensitivity and specificity of macrocytosis and hypochromasia for detecting regenerative anemia (RA), and to evaluate the association of anemia with increased serum creatinine concentration (SC). STUDY POPULATION: Laboratory records from 30,503 blood samples from cats (2003-2011).
methodsClinicopathologic data reviewed retrospectively. Anemia defined as hematocrit (Ht) ≤27%, red blood cell count (RBC) ≤5.5 × 10(6)/μL and hemoglobin (Hb) ≤9.0 g/dL. RA defined by manual absolute reticulocyte count >50 × 10(3)/μL. Macrocytosis was defined as mean corpuscular volume (MCV) >55 fL and hypochromasia as mean corpuscular hemoglobin concentration (MCHC) <31 g/dL. Cutoff for increased serum creatinine concentration was 1.6 mg/dL.
resultsOverall, 1,098 of 30,503 blood samples (3.6%) from cats fulfilled criteria for anemia, 633 of 1,098 (57.7%) classified as nonregenerative (NRA) and 465 of 1,098 (42.3%) as regenerative. RBC, Ht, and Hb were significantly lower in the RA compared to NRA group (P < .05). Sensitivity and specificity of the combined high MCV and low MCHC to detect samples with RA were 19.5 and 90.7%. SC was increased in 572 of the 1,098 anemic samples (52.1%) and in 11,121 of 29,405 of nonanemic samples (37.8%). CONCLUSIONS AND CLINICAL IMPORTANCE: Majority of anemic samples were classified as NRA. Anemia was more severe in cats with RA. Erythrocyte indices were not sensitive indicators of RA.
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