ArticleJournal of neurophysiology2015
Generation of field potentials and modulation of their dynamics through volume integration of cortical activity.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Traveling waves along the cortical depth reflect structured synaptic inputs.Research square · 2026Article
- Spectrotemporal signatures of driving and modulatory circuits across cortical and subcortical networks.bioRxiv : the preprint server for biology · 2026Article
- Spectrotemporal signatures of driving- and modulatory circuits across cortical and subcortical networks.Frontiers in human neuroscience · 2026Article
- Layers of the monkey visual cortex are selectively modulated during electrical stimulation.PLoS biology · 2025Article
- Pattern-pulses and pattern-reversals evoke different cascades of cortical sources in the multifocal visual evoked potential.Journal of vision · 2025Article
- Large-scale interactions in predictive processing: oscillatory versus transient dynamics.Trends in cognitive sciences · 2025Review
- Electroanatomy of hippocampal activity patterns: theta, gamma waves, sharp wave-ripples, and dentate spikes.Frontiers in behavioral neuroscience · 2025Article
- Laminar pattern of sensory-evoked dynamic high-frequency oscillatory activity in the macaque auditory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Acoustic and language-specific sources for phonemic abstraction from speech.Nature communications · 2024Article
- The Spatial Reach of Neuronal Coherence and Spike-Field Coupling across the Human Neocortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Magnifying Traveling Waves on the Scalp.Brain topography · 2022Article
- Cross Laminar Traveling Components of Field Potentials due to Volume Conduction of Non-Traveling Neuronal Activity in Macaque Sensory Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- The Role of Motor and Environmental Visual Rhythms in Structuring Auditory Cortical Excitability.iScience · 2020Article
- Dissociation of broadband high-frequency activity and neuronal firing in the neocortex.Science advances · 2020Article
- Impact of Brain Surface Boundary Conditions on Electrophysiology and Implications for Electrocorticography.Frontiers in neuroscience · 2020Article
- Theta Oscillations Alternate With High Amplitude Neocortical Population Within Synchronized States.Frontiers in neuroscience · 2019Article
- Top-down, contextual entrainment of neuronal oscillations in the auditory thalamocortical circuit.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Distinct frequency bands in the local field potential are differently tuned to stimulus drift rate.Journal of neurophysiology · 2018Article
- Superficial Slow Rhythms Integrate Cortical Processing in Humans.Scientific reports · 2018Article
- Signatures of Somatic Inhibition and Dendritic Excitation in Auditory Brainstem Field Potentials.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
Corrections and comments
- Erratum issuedCorrigendum.2015
Authors and funding
2 authors.
Funding
Abstract
Field potentials (FPs) recorded within the brain, often called "local field potentials" (LFPs), are useful measures of net synaptic activity in a neuronal ensemble. However, due to volume conduction, FPs spread beyond regions of underlying synaptic activity, and thus an "LFP" signal may not accurately reflect the temporal patterns of synaptic activity in the immediately surrounding neuron population. To better understand the physiological processes reflected in FPs, we explored the relationship between the FP and its membrane current generators using current source density (CSD) analysis in conjunction with a volume conductor model. The model provides a quantitative description of the spatiotemporal summation of immediate local and more distant membrane currents to produce the FP. By applying the model to FPs in the macaque auditory cortex, we have investigated a critical issue that has broad implications for FP research. We have shown that FP responses in particular cortical layers are differentially susceptible to activity in other layers. Activity in the supragranular layers has the strongest contribution to FPs in other cortical layers, and infragranular FPs are most susceptible to contributions from other layers. To define the physiological processes generating FPs recorded in loci of relatively weak synaptic activity, strong effects produced by synaptic events in the vicinity have to be taken into account. While outlining limitations and caveats inherent to FP measurements, our results also suggest specific peak and frequency band components of FPs can be related to activity in specific cortical layers. These results may help improving the interpretability of FPs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.