Evidence map›Paper›PMID 25274108›Full record

ArticleCurrent Alzheimer research2014

Association of smoking and alcohol drinking with dementia risk among elderly men in China.

Shiming Zhou, Rui Zhou, Tingting Zhong, Rui Li, Jun Tan, Huadong Zhou

Open access · bronzeAbstract read
In one paragraph

Article in Current Alzheimer research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shiming Zhou
Rui Zhou
Tingting Zhong
Rui Li
Jun Tan
Huadong ZhouDepartment of Neurology, Daping hospital, Third Military Medical University, Chongqing, 400038, P.R. China. zhouhuad@163.com.
Daping Hospital · CNArmy Medical University · CNUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies relating smoking and alcohol drinking with the incidence of dementia have been inconsistent.

objectivesWe assessed whether smoking and alcohol drinking was associated with the risk of dementia, including Alzheimer disease (AD) and vascular dementia (VaD) after seven years of follow-up.

designWe prospectively analysed the incidence of dementia from 2004 to 2011 among 2959 elderly men, according to their smoking and alcohol drinking status.

settingsix neighbourhoods from three districts mentioned in Chongqing city.

participantsA total of 3170 men were followed up annually for 7 years. MEASUREMENTS: Cox proportional hazards models were established to evaluate the association between smoking, alcohol drinking and the risk of dementia.

resultsThe incidences of AD and VaD were higher respectively in current smoking than never smoking, daily drinking than never drinking over 7 years of follow-up (p<0.01). After adjusting for age and other potential confounders, current smoking was associated with increased risk of AD (HR= 2.14, 95% CI 1.20-4.46) and VaD (HR= 3.28, 95% CI 1.14-4.52), meanwhile, daily drinking was related to increased risk of AD (HR= 2.25, 95% CI 1.43-3.97) and VaD (HR= 3.42, 95% CI 1.18-4.51). In addition, co-smoking and drinking were related to with a significantly higher risk of AD and VaD than non-smoking and drinking (HR= 3.03, 95% CI 1.65-4.19) and VaD (HR= 3.96, 95% CI 1.64-4.71). Moreover, co-smoking and drinking had higher risk of AD and VaD compared with current smoking and daily drinking.

conclusionsCurrent smoking and daily drinking were found to be significantly associated with dementia in elderly men.

Indexed as

AgedAlcohol DrinkingChinaDementiaFollow-Up StudiesHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRiskSmoking

Identifiers

PMID25274108
PMCPMC4428477
OpenAlexW2114133002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.