Evidence map›Paper›PMID 25273813›Full record

ArticleBMJ open2014

Prevalence, nature and predictors of prescribing errors in mental health hospitals: a prospective multicentre study.

Richard N Keers, Steven D Williams, Joe J Vattakatuchery, Petra Brown, Joan Miller, Lorraine Prescott, Darren M Ashcroft

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  15. Associations of physicians' prescribing experience, work hours, and workload with prescription errors.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
  16. Article
  17. Comparison of pharmacy technicians' and doctors' medication transcribing errors at hospital discharge.European journal of hospital pharmacy : science and practice · 2020
    Article
  18. Review
  19. Observational
  20. A collaborative evaluation of pharmacy interventions in the care of inpatients in community hospitals.European journal of hospital pharmacy : science and practice · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Richard N KeersCentre for Pharmacoepidemiology and Drug Safety, Manchester Pharmacy School, Manchester Academic Health Sciences Centre (MAHSC), University of Manchester, Manchester, UK NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, MAHSC, University of Manchester, Manchester, UK.
Steven D WilliamsCentre for Pharmacoepidemiology and Drug Safety, Manchester Pharmacy School, Manchester Academic Health Sciences Centre (MAHSC), University of Manchester, Manchester, UK Pharmacy Department, University Hospital of South Manchester NHS Foundation Trust, MAHSC, Manchester, UK.
Joe J VattakatucheryAdult Services Warrington, 5 Boroughs Partnership NHS Foundation Trust, Warrington, Cheshire, UK Medical School, University of Liverpool, Liverpool, UK.
Petra BrownPharmacy Department, Manchester Mental Health and Social Care NHS Trust, MAHSC, Manchester, UK.
Joan MillerPharmacy Department, Greater Manchester West Mental Health NHS Foundation Trust, Salford, UK.
Lorraine PrescottMedicines Management Team, 5 Boroughs Partnership NHS Foundation Trust, Warrington, Cheshire, UK.
Darren M AshcroftCentre for Pharmacoepidemiology and Drug Safety, Manchester Pharmacy School, Manchester Academic Health Sciences Centre (MAHSC), University of Manchester, Manchester, UK NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, MAHSC, University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence, nature and predictors of prescribing errors (PEs) in three mental health hospitals.

settingInpatient units in three National Health Service (NHS) mental health hospitals in the North West of England.

participantsTrained clinical pharmacists prospectively recorded the number of PEs in newly written or omitted prescription items screened during their routine work on 10 data collection days. A multidisciplinary panel reviewed PE data using established methods to confirm (1) the presence of a PE, (2) the type of PE and (3) whether errors were clinically relevant and likely to cause harm. PRIMARY OUTCOME MEASURES: Frequency, nature and predictors of PEs.

resultsOf 4427 screened prescription items, 281 were found to have one or more PEs (error rate 6.3% (95% CI 5.6 to 7.1%)). Multivariate analysis revealed that specialty trainees (OR 1.23 (1.01 to 1.51)) and staff grade psychiatrists (OR 1.50 (1.05 to 2.13)) were more likely to make PEs when compared to foundation year (FY) one doctors, and that specialty trainees and consultant psychiatrists were twice as likely to make clinically relevant PEs (OR 2.61 (2.11 to 3.22) and 2.03 (1.66 to 2.50), respectively) compared to FY one staff. Prescription items screened during the prescription chart rewrite (OR 0.52 (0.33 to 0.82)) or at discharge (OR 0.87 (0.79 to 0.97)) were less likely to be associated with PEs than items assessed during inpatient stay, although they were more likely to be associated with clinically relevant PEs (OR 2.27 (1.72 to 2.99) and 4.23 (3.68 to 4.87), respectively). Prescription items screened at hospital admission were five times more likely (OR 5.39 (2.72 to 10.69)) to be associated with clinically relevant errors than those screened during patient stay.

conclusionsPEs may be more common in mental health hospitals than previously reported and important targets to minimise these errors have been identified.

Indexed as

Drug PrescriptionsEnglandFemaleHospitals, PsychiatricHumansMaleMedication ErrorsMental DisordersPrevalenceProspective StudiesPsychotropic DrugsRisk FactorsPsychotropic DrugsPSYCHIATRY

Identifiers

PMID25273813
PMCPMC4185335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.